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Enhancing rAAV vector expression in the lung
Isabel Virella-Lowell
, Benjamin Zusman
, Kevin Foust
, Scott Loiler
, Thomas Conlon
, Sihong Song
, Kye A. Chesnut
, Thomas Ferkol
, Terence R. Flotte
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Division of Allergy & Pulmonary Medicine
Research output
:
Contribution to journal
›
Article
›
peer-review
58
Scopus citations
Overview
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Keyphrases
Lung
100%
Recombinant Adeno-associated Virus (rAAV)
100%
Gene Expression
50%
Cytomegalovirus
50%
Luciferase
50%
Alpha-1 Antitrypsin
50%
Relative Light Units
50%
AAV Capsid
50%
Gene Therapy
25%
Transcriptional Regulatory Elements
25%
Serum Levels
25%
Capsid
25%
Chicken
25%
Gene Transfer
25%
Tropism
25%
Serotype 1
25%
Immediate Early
25%
Cystic Fibrosis
25%
Coding Sequence
25%
Post-transcriptional
25%
Transfer Efficiency
25%
Actin Gene
25%
Airway Cells
25%
Cassette
25%
Relative Activity
25%
Apical Surface
25%
Strong Promoter
25%
Cystic Fibrosis Transmembrane Conductance Regulator
25%
Serotype 5
25%
Promoter Elements
25%
Serotype 2
25%
DNA Transfer
25%
Wide Dynamic Range
25%
Endogenous Promoter
25%
Woodchuck Hepatitis Virus
25%
Secreted Reporter
25%
Medicine and Dentistry
Promoter Region
100%
Expression Vector
100%
Lung
100%
Serotype
57%
Adeno-Associated Virus
42%
Virus Capsid
42%
Gene Expression
28%
Cystic Fibrosis
28%
Cytomegalovirus
28%
Luciferase
28%
Alpha 1 Antitrypsin
28%
In Vitro
14%
Actin
14%
Gene Therapy
14%
Gene Transfer
14%
Enhancer Region
14%
Airway Cell
14%
Woodchuck Hepatitis Virus
14%
Transfer DNA
14%
Biochemistry, Genetics and Molecular Biology
Promoter Region
100%
Expression Vector
100%
Serotype
66%
Capsid
50%
Gene Expression
33%
Luciferase
33%
Cystic Fibrosis
33%
Alpha 1-Antitrypsin
33%
Cytomegalovirus
33%
Enhancer Region
16%
Gene Therapy
16%
Blood Level
16%
Actin
16%
Adeno Associated Virus
16%
Pribnow Box
16%
Transfer DNA
16%
Woodchuck Hepatitis Virus
16%
Transcriptional Regulatory Element
16%
Pharmacology, Toxicology and Pharmaceutical Science
Cystic Fibrosis
100%
Luciferase
100%
Cytomegalovirus
100%
Alpha 1 Antitrypsin
100%
Gene Delivery
50%
Actin
50%
Adeno Associated Virus
50%
Woodchuck Hepatitis Virus
50%
Immunology and Microbiology
Promoter Region
100%
Expression Vector
100%
Serotype
57%
Capsid
42%
Gene Expression
28%
Cytomegalovirus
28%
Alpha 1-Antitrypsin
28%
Adeno-Associated Virus
28%
Blood Level
14%
Gene Transfer
14%
Actin
14%
Enhancer Region
14%
Adeno Associated Virus
14%
DNA Transfer
14%
Airway Cell
14%
Woodchuck Hepatitis Virus
14%
In Vitro
14%