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Enhanced tumor recognition and killing using the HSV-TK suicide gene
R. Ramesh
, S. M. Freeman
, A. Munshi
, C. N. Abboud
, A. J. Marrogi
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Research output
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Article
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peer-review
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Keyphrases
Thymidine Kinase Gene
100%
Suicide Gene
100%
Herpes Simplex Virus Thymidine Kinase
100%
Tumor Killing
100%
Tumor Recognition
100%
Tumor
44%
Gene-gene
44%
Tumor Cells
33%
Gene-modified Cells
33%
Quantitative PCR
22%
Costimulatory Molecules
22%
B7-2
22%
B7-1
22%
Tumor-infiltrating Lymphocytes
22%
Bystander Effect
22%
Gene Treatment
22%
Interleukin-1β
11%
Tumor Necrosis Factor-α
11%
Immunohistochemistry
11%
Interleukin-6
11%
Macrophages
11%
T Cells
11%
Syngeneic
11%
Cancer Treatment
11%
In Vivo Analysis
11%
Interleukin-2
11%
Inoculation
11%
Tumor Microenvironment
11%
Cytokine Cascade
11%
Murine Tumor Model
11%
Tumor Necrosis
11%
ICAM
11%
Gene-modified
11%
Tumor Infiltrating Mononuclear Cells
11%
Post Inoculation
11%
IFN-y
11%
Semi-quantitative PCR
11%
Immunology and Microbiology
Herpes Simplex Virus
100%
Suicide Gene
100%
Phosphotransferase
100%
Kinase
100%
Tumor Cell
33%
Cytokine
22%
Tumor Necrosis Factor
22%
Tumor-Associated Macrophage
22%
Bystander Effect
22%
Reverse Transcription Polymerase Chain Reaction
22%
T Cell
11%
Cerebrospinal Fluid
11%
Macrophage
11%
Real-Time Polymerase Chain Reaction
11%
Interleukin 1
11%
Interleukin 6
11%
Syngenic
11%
Interleukin 2
11%
Mononuclear Cell
11%
Intercellular Adhesion Molecule
11%
Neuroscience
Herpes Simplex Virus
100%
Thymidine Kinase
100%
Suicide Gene
100%
In Vivo
22%
Bystander Effect
22%
Lymphocyte
22%
Reverse Transcription Polymerase Chain Reaction
22%
Cytokine
22%
Immunohistochemistry
11%
Real-Time Polymerase Chain Reaction
11%
Macrophage
11%
Interleukin 6
11%
T Cell
11%
Interleukin 1
11%
Necrosis
11%
Interleukin 2
11%
Messenger RNA
11%