TY - JOUR
T1 - Endovascular therapy for advanced post-thrombotic syndrome
T2 - Proceedings from a multidisciplinary consensus panel
AU - Vedantham, Suresh
AU - Kahn, Susan R.
AU - Goldhaber, Samuel Z.
AU - Comerota, Anthony J.
AU - Parpia, Sameer
AU - Meleth, Sreelatha
AU - Earp, Diane
AU - Williams, Rick
AU - Sista, Akhilesh K.
AU - Marston, William
AU - Rathbun, Suman
AU - Magnuson, Elizabeth A.
AU - Razavi, Mahmood K.
AU - Jaff, Michael R.
AU - Kearon, Clive
N1 - Funding Information:
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: the expert panel meeting and manuscript development were supported by grants U34-HL123831 and U24-HL114577 from the National Heart, Lung, and Blood Institute (NHLBI). The views expressed are those of the authors and do not represent the NHLBI or National Institutes of Health.
Publisher Copyright:
© SAGE Publications.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Patients with advanced post-thrombotic syndrome (PTS) and chronic iliac vein obstruction suffer major physical limitations and impairment of health-related quality of life. Currently there is a lack of evidence-based treatment options for these patients. Early studies suggest that imaging-guided, catheter-based endovascular therapy can eliminate iliac vein obstruction and saphenous venous valvular reflux, resulting in reduced PTS severity; however, these observations have not been rigorously validated. A multidisciplinary expert panel meeting was convened to plan a multicenter randomized controlled clinical trial to evaluate endovascular therapy for the treatment of advanced PTS. This article summarizes the findings of the panel, and is expected to assist in developing a National Institutes of Health-sponsored clinical trial and other studies to improve the care of patients with advanced PTS.
AB - Patients with advanced post-thrombotic syndrome (PTS) and chronic iliac vein obstruction suffer major physical limitations and impairment of health-related quality of life. Currently there is a lack of evidence-based treatment options for these patients. Early studies suggest that imaging-guided, catheter-based endovascular therapy can eliminate iliac vein obstruction and saphenous venous valvular reflux, resulting in reduced PTS severity; however, these observations have not been rigorously validated. A multidisciplinary expert panel meeting was convened to plan a multicenter randomized controlled clinical trial to evaluate endovascular therapy for the treatment of advanced PTS. This article summarizes the findings of the panel, and is expected to assist in developing a National Institutes of Health-sponsored clinical trial and other studies to improve the care of patients with advanced PTS.
KW - deep vein thrombosis
KW - endovascular therapy
KW - post-thrombotic syndrome
KW - quality of life
KW - stent
UR - http://www.scopus.com/inward/record.url?scp=84979584071&partnerID=8YFLogxK
U2 - 10.1177/1358863X16650747
DO - 10.1177/1358863X16650747
M3 - Article
C2 - 27247235
AN - SCOPUS:84979584071
SN - 1358-863X
VL - 21
SP - 400
EP - 407
JO - Vascular Medicine (United Kingdom)
JF - Vascular Medicine (United Kingdom)
IS - 4
ER -