Endothelial cell prostaglandin I₂ and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A₂β knockout mouse

Keyphrases

• Knock-in Mouse Model 100%
• Endothelial Cells 100%
• Calcium-independent Phospholipase A2 100%
• Prostaglandins 100%
• Platelet-activating Factor 100%
• IPLA2 83%
• Arachidonic Acid Release 83%
• Tryptase 33%
• Thrombin 33%
• Lung Epithelial Cells 33%
• Inflammatory Cell Infiltration 33%
• Knockout Cell Lines 33%
• Lung 16%
• Wild Mice 16%
• Airway 16%
• Therapeutic Target 16%
• Cell Membrane 16%
• Selective Inhibitor 16%
• Membrane Phospholipids 16%
• Bromoenol Lactone 16%
• Phospholipase A2 (PLA2) 16%
• Phospholipase A2 Activity 16%
• Airway Inflammation 16%
• Platelet-activating Factor Receptor 16%
• Interstitium 16%
• Inflammatory Lung Disease 16%
• Circulating Cells 16%
• Lung Endothelium 16%
• Human Microvascular Endothelial Cells 16%
• PLA2 Activity 16%
• Interstitial Edema 16%
• Phospholipid Hydrolysis 16%

Biochemistry, Genetics and Molecular Biology

• Knockout Mouse 100%
• Phospholipase A2 100%
• Platelet-Activating Factor 100%
• Prostacyclin 100%
• Wild Type 50%
• Arachidonic Acid 50%
• Tryptase 33%
• Thrombin 33%
• Wild Type Mouse 16%
• Enzymatic Hydrolysis 16%
• Cell Membrane 16%
• Metabolite 16%
• Platelet-Activating Factor Receptor 16%
• Phospholipid 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Knockout Mouse 100%
• Prostacyclin 100%
• Calcium Independent Phospholipase A2 100%
• Thrombocyte Activating Factor 100%
• Arachidonic Acid 42%
• Tryptase 28%
• Phospholipase A2 28%
• Thrombin 28%
• Wild Type Mouse 14%
• Membrane Phospholipid 14%
• Bromoenol Lactone 14%
• Edema 14%
• Respiratory Tract Inflammation 14%
• Thrombocyte Activating Factor Receptor 14%
• Diseases 14%