Endoscopic ultrasound-fine needle injection for oncological therapy

Jeremy Kaplan, Amaara Khalid, Natalie Cosgrove, Ayesha Soomro, Syed Mohsin Mazhar, Ali A. Siddiqui

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The minimal invasiveness and precision of endoscopic ultrasound (EUS) has lead to both its widespread use as a diagnostic and staging modality for gastrointestinal and pancreaticobiliary malignancies, and to its expanding role as a therapeutic modality. EUS-guided celiac plexus neurolysis is now a well-accepted modality for palliation of pain in patients with pancreatic cancer. EUS-guided ablation, brachytherapy, fiducial marker placement, and antitumor agent injection have been described as methods of performing minimally invasive oncological therapy. EUS-fine needle injection may be performed as adjunctive, alternative, or palliative treatment. This review summarizes the studies to date that have described these methods. A literature search using the PubMed/MEDLINE databases was performed. While most published studies to date are limited with disappointing outcomes, the concept of a role of EUS in oncological therapy seems promising.

Original languageEnglish
Pages (from-to)466-472
Number of pages7
JournalWorld Journal of Gastrointestinal Oncology
Issue number12
StatePublished - Dec 15 2015


  • Cryothermal ablation
  • Endoscopic ultrasound-fine needle injection
  • Endoscopic ultrasound-guided ablation
  • Endoscopic ultrasound-guided antitumor agent injection
  • Endoscopic ultrasound-guided brachytherapy
  • Fiducial markers
  • Photodynamic therapy
  • Radiofrequency ablation


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