Abstract
Gastroesophageal reflux disease (GERD) is a condition with increasing prevalence and morbidity in the United States and worldwide. Despite advances in medical and surgical therapy over the last 30 years, gaps remain in the therapeutic profile of options. Flexible upper endoscopy offers the promise of filling in these gaps in a potentially minimally invasive approach. In this concise review, we focus on the plethora of endoluminal therapies available for the treatment of GERD. Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. As new endoscopic treatments become available, we come closer to the promise of the incisionless treatment of GERD. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.
Original language | English |
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Pages (from-to) | 121-129 |
Number of pages | 9 |
Journal | Annals of the New York Academy of Sciences |
Volume | 1482 |
Issue number | 1 |
DOIs | |
State | Published - Dec 10 2020 |
Keywords
- GERD
- emerging technology
- endoscopic therapy
- flexible endoscopy