Endoscopic treatments for GERD

Bradley S. Kushner, Michael M. Awad, Dean J. Mikami, Bipan B. Chand, Christina J. Wai, Kenric M. Murayama

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Gastroesophageal reflux disease (GERD) is a condition with increasing prevalence and morbidity in the United States and worldwide. Despite advances in medical and surgical therapy over the last 30 years, gaps remain in the therapeutic profile of options. Flexible upper endoscopy offers the promise of filling in these gaps in a potentially minimally invasive approach. In this concise review, we focus on the plethora of endoluminal therapies available for the treatment of GERD. Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. As new endoscopic treatments become available, we come closer to the promise of the incisionless treatment of GERD. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.

Original languageEnglish
Pages (from-to)121-129
Number of pages9
JournalAnnals of the New York Academy of Sciences
Issue number1
StatePublished - Dec 10 2020


  • GERD
  • emerging technology
  • endoscopic therapy
  • flexible endoscopy


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