Endometriosis

Dan I. Lebovic; Tommaso Falcone

doi:10.1007/9783319522104_24

Endometriosis

Dan I. Lebovic
, Tommaso Falcone

Division of Reproductive Endocrinology & Infertility

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Endometriosis is a chronic gynecologic disease with a pleiotropic symptomatology, physical presentation, and treatment approaches. Ten percent of the population is affected; however, the prevalence in chronic pelvic pain or infertility-stricken women is much higher. Surgical diagnosis is adequate, but the classification scheme is of little value to clinicians. Apart from a genetic component to endometriosis, there are other predisposing factors that are predominately estrogen driven. Several hypotheses exist, but there is no conclusive theory for either the pathophysiology of endometriosis or the mechanisms for attributed infertility and pain. This chapter describes approaches to treating infertility (both surgically and medically) as well as managing pain symptoms. As much as the literature provides, evidence-based studies have been summarized to maximize your treatment approaches to this vexing disease.

Original language	English
Title of host publication	Clinical Reproductive Medicine and Surgery
Subtitle of host publication	A Practical Guide
Publisher	Springer International Publishing
Pages	433-446
Number of pages	14
ISBN (Electronic)	9783319522104
ISBN (Print)	9783319522098
DOIs	https://doi.org/10.1007/9783319522104_24
State	Published - Jan 1 2017

Keywords

Chronic pelvic pain
Deep endometriosis
Endometrial cells are found outside the uterus and lead to symptoms such as severe pelvic pain, dysmenorrhea, dyspareunia, and subfertility
Endometrial tissue located at sites outside of the uterus during the embryologic period of organogenesis
Endometrioma
Endometriosis
Müllerianosis
Ovarian cyst lined by endometrial tissue and containing thick, brown, tar-like fluid
Pain below the umbilicus that is of at least 6 months’ duration and causes functional disability
Reduced fertility over a prolonged period of time
Retrograde menstruum exits through the fallopian tubes into the pelvis and in some women this could eventually lead to the development and establishment of endometriosis
Sampson’s theory
Subfertility
When the endometrial tissue invades deeper than 5 mm

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10.1007/9783319522104_24

Cite this

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Endometriosis

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