Endolymphatic sac tumors

Cameron C. Wick, Nauman F. Manzoor, Maroun T. Semaan, Cliff A. Megerian

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial neuropathies. Management is primarily via microsurgical excision. Radiation therapy has a limited role for residual or unresectable disease. Early detection may enable hearing preservation techniques. ELST have an association with von Hippel-Lindau disease.

Original languageEnglish
Pages (from-to)317-330
Number of pages14
JournalOtolaryngologic Clinics of North America
Volume48
Issue number2
DOIs
StatePublished - Apr 1 2015
Externally publishedYes

Keywords

  • Endolymphatic sac tumors
  • Hearing preservation
  • Meniere syndrome
  • Von Hippel-Lindau

Fingerprint Dive into the research topics of 'Endolymphatic sac tumors'. Together they form a unique fingerprint.

  • Cite this

    Wick, C. C., Manzoor, N. F., Semaan, M. T., & Megerian, C. A. (2015). Endolymphatic sac tumors. Otolaryngologic Clinics of North America, 48(2), 317-330. https://doi.org/10.1016/j.otc.2014.12.006