Endolymphatic sac tumors

Cameron C. Wick; Nauman F. Manzoor; Maroun T. Semaan; Cliff A. Megerian

doi:10.1016/j.otc.2014.12.006

Endolymphatic sac tumors

Cameron C. Wick, Nauman F. Manzoor, Maroun T. Semaan, Cliff A. Megerian

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial neuropathies. Management is primarily via microsurgical excision. Radiation therapy has a limited role for residual or unresectable disease. Early detection may enable hearing preservation techniques. ELST have an association with von Hippel-Lindau disease.

Original language	English
Pages (from-to)	317-330
Number of pages	14
Journal	Otolaryngologic Clinics of North America
Volume	48
Issue number	2
DOIs	https://doi.org/10.1016/j.otc.2014.12.006
State	Published - Apr 1 2015

Keywords

Endolymphatic sac tumors
Hearing preservation
Meniere syndrome
Von Hippel-Lindau

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10.1016/j.otc.2014.12.006

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title = "Endolymphatic sac tumors",

abstract = "Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial neuropathies. Management is primarily via microsurgical excision. Radiation therapy has a limited role for residual or unresectable disease. Early detection may enable hearing preservation techniques. ELST have an association with von Hippel-Lindau disease.",

keywords = "Endolymphatic sac tumors, Hearing preservation, Meniere syndrome, Von Hippel-Lindau",

author = "Wick, {Cameron C.} and Manzoor, {Nauman F.} and Semaan, {Maroun T.} and Megerian, {Cliff A.}",

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AU - Wick, Cameron C.

AU - Manzoor, Nauman F.

AU - Semaan, Maroun T.

AU - Megerian, Cliff A.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial neuropathies. Management is primarily via microsurgical excision. Radiation therapy has a limited role for residual or unresectable disease. Early detection may enable hearing preservation techniques. ELST have an association with von Hippel-Lindau disease.

AB - Endolymphatic sac tumors (ELST) are slow-growing, locally aggressive, low-grade malignancies that originate from the epithelium of the endolymphatic duct and sac. ELST often present with sensorineural hearing loss, tinnitus, and vertigo, which may mimic Meniere disease. Large tumors may present with additional cranial neuropathies. Management is primarily via microsurgical excision. Radiation therapy has a limited role for residual or unresectable disease. Early detection may enable hearing preservation techniques. ELST have an association with von Hippel-Lindau disease.

KW - Endolymphatic sac tumors

KW - Hearing preservation

KW - Meniere syndrome

KW - Von Hippel-Lindau

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DO - 10.1016/j.otc.2014.12.006

M3 - Review article

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SN - 0030-6665

VL - 48

SP - 317

EP - 330

JO - Otolaryngologic Clinics of North America

JF - Otolaryngologic Clinics of North America

IS - 2

ER -

Endolymphatic sac tumors

Abstract

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