Endogenous Pseudallescheria boydii Endophthalmitis: Clinicopathologic Findings in Two Cases

John D. Pfeifer, M. Gilbert Grand, Matthew A. Thomas, Alan R. Berger, Markj Lucarelli, Morton E. Smith

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28 Scopus citations


Two cases of endogenous Pseudallescheria boydii endophthalmitis are presented. One patient had severe pulmonary fibrosis but no history of ocular trauma and no clinical or laboratory evidence of immunocompromise. Despite therapy with repeated intravitreal miconazole nitrate injections and systemic fluconazole, enucleation of the globe was required, and the patient eventually died with disseminated pseudallescheriasis. The other patient was an immunosuppressed cardiac transplant recipient who also received systemic fluconazole therapy. The infected eye eventually required evisceration, but there was no evidence of disseminated pseudallescheriasis before his death of unrelated causes.

Original languageEnglish
Pages (from-to)1714-1717
Number of pages4
JournalArchives of Ophthalmology
Issue number12
StatePublished - Dec 1991


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