TY - JOUR
T1 - Empirical evaluation of language disorder in schizophrenia
AU - Stephane, Massoud
AU - Pellizzer, Giuseppe
AU - Fletcher, Charles R.
AU - McClannahan, Kate
N1 - Funding Information:
We received grant support from the VA Medical Center, the Minnesota Medical Foundation and the MIND Institute. We thank Christa Surerus-Johnson for the clinical evaluation of subjects included in this study.
PY - 2007/7
Y1 - 2007/7
N2 - Objective: Studies of the content of speech and of verbal hallucinations in schizophrenia point to dysfunction at multiple levels of language. In this study, we empirically evaluated language processes. Methods: We examined the performance of 22 schizophrenia patients and 11 healthy control subjects with procedures designed to explore the sublexical, lexical, semantic, syntactic and discourse levels of language processing. Results: Schizophrenia patients exhibit impairment in the recognition of incorrect, but not correct, linguistic stimuli at all but the sublexical level of language processing. The patients were not impaired in the recognition of nonlinguistic stimuli. Conclusion: This language-specific differential impairment could explain speech abnormalities in schizophrenia. The nonrecognition of incorrect linguistic information would prevent patients from correcting the abnormal speech they may occasionally produce. A model of decreased power of linguistic computations (reduced number of operations) adequately accounts for this differential impairment.
AB - Objective: Studies of the content of speech and of verbal hallucinations in schizophrenia point to dysfunction at multiple levels of language. In this study, we empirically evaluated language processes. Methods: We examined the performance of 22 schizophrenia patients and 11 healthy control subjects with procedures designed to explore the sublexical, lexical, semantic, syntactic and discourse levels of language processing. Results: Schizophrenia patients exhibit impairment in the recognition of incorrect, but not correct, linguistic stimuli at all but the sublexical level of language processing. The patients were not impaired in the recognition of nonlinguistic stimuli. Conclusion: This language-specific differential impairment could explain speech abnormalities in schizophrenia. The nonrecognition of incorrect linguistic information would prevent patients from correcting the abnormal speech they may occasionally produce. A model of decreased power of linguistic computations (reduced number of operations) adequately accounts for this differential impairment.
KW - Language
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=34447319170&partnerID=8YFLogxK
M3 - Article
C2 - 17653293
AN - SCOPUS:34447319170
SN - 1180-4882
VL - 32
SP - 250
EP - 258
JO - Journal of Psychiatry and Neuroscience
JF - Journal of Psychiatry and Neuroscience
IS - 4
ER -