Emerging therapy for the treatment of mantle cell lymphoma

Saurabh Rajguru, Brad S. Kahl

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Mantle cell lymphoma (MCL) is a heterogenous disease with historically relative poor outcomes. However, new treatment strategies seem to be improving the prognosis for patients. Although no universally accepted standard of care exists, options for patients with newly diagnosed MCL include intensive and nonintensive strategies. Generally, intensive strategies produce more durable remissions and are selected for younger patients, whereas nonintensive strategies are most appropriate for older patients or patients with comorbidities. However, new options are closing the treatment gap between intensive and nonintensive strategies. Treatment options are also increasing for patients with relapsed/refractory MCL and include agents targeting the microenvironment and the B-cell receptor signaling pathway.

Original languageEnglish
Pages (from-to)1311-1318
Number of pages8
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number9
StatePublished - Sep 1 2014


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