TY - JOUR
T1 - Embryonal rhabdomyosarcoma with a novel t(2;6)(p23;p21.1)
AU - Pressey, Joseph G.
AU - Mroczek-Musulman, Elizabeth
AU - Murata-Collins, Joyce L.
AU - Saito, Jacqueline M.
AU - Hammers, Yuki
PY - 2008/11/1
Y1 - 2008/11/1
N2 - Chromosomal translocations are infrequently encountered in embryonal rhabdomyosarcoma (E-RMS). Here, we present a case of an infant with a chest wall E-RMS in which t(2;6)(p23;p21.1) was detected. Despite the involvement of the 2p23 locus in the translocation, the tumor did not express ALK. The t(2;6)(p23;p21.1) is a novel finding in E-RMS that may provide insight into the pathogenesis of this relatively frequent childhood tumor.
AB - Chromosomal translocations are infrequently encountered in embryonal rhabdomyosarcoma (E-RMS). Here, we present a case of an infant with a chest wall E-RMS in which t(2;6)(p23;p21.1) was detected. Despite the involvement of the 2p23 locus in the translocation, the tumor did not express ALK. The t(2;6)(p23;p21.1) is a novel finding in E-RMS that may provide insight into the pathogenesis of this relatively frequent childhood tumor.
UR - http://www.scopus.com/inward/record.url?scp=55049125886&partnerID=8YFLogxK
U2 - 10.1016/j.cancergencyto.2008.07.007
DO - 10.1016/j.cancergencyto.2008.07.007
M3 - Article
C2 - 18992640
AN - SCOPUS:55049125886
VL - 187
SP - 39
EP - 42
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1
ER -