Elimination of medically intractable epileptic drop attacks following endoscopic total corpus callosotomy in Rett syndrome

Keisuke Ueda, Sandeep Sood, Eishi Asano, Ajay Kumar, Aimee F. Luat

Research output: Contribution to journalArticle

Abstract

Introduction: Rett syndrome is a neurodevelopmental genetic disorder, characterized by developmental delay, hand stereotypies, abnormal gait, and acquired microcephaly. Epilepsy is very common in Rett syndrome and can be medically intractable. It remains uncertain if a patient with epileptic drop attacks associated with this genetic disease can benefit from corpus callosotomy. Case report: We report an 8-year-old girl with Rett syndrome and medically intractable epileptic drop attacks who underwent endoscopic total corpus callosotomy without any complications that led to the successful elimination of her seizures. Conclusion: Total corpus callosotomy is a feasible treatment option for medically intractable epileptic drop attacks in Rett syndrome and should not be considered as a contraindication in this condition. This is the first reported case of corpus callosotomy in Rett syndrome.

Original languageEnglish
Pages (from-to)1883-1887
Number of pages5
JournalChild's Nervous System
Volume33
Issue number11
DOIs
StatePublished - Nov 1 2017
Externally publishedYes

Keywords

  • Drop attack
  • Endoscopic neurosurgery
  • Rett syndrome
  • Total corpus callosotomy

Fingerprint Dive into the research topics of 'Elimination of medically intractable epileptic drop attacks following endoscopic total corpus callosotomy in Rett syndrome'. Together they form a unique fingerprint.

  • Cite this