TY - JOUR
T1 - Elevated Serum Interleukin-2 Levels in Chronic Progressive Multiple Sclerosis
AU - Trotter, John L.
AU - Clifford, David B.
AU - Anderson, Charles B.
AU - Van Der Veen, Roel C.
AU - Hicks, Byron C.
AU - Banks, Geneva
PY - 1988/5/5
Y1 - 1988/5/5
N2 - To the Editor: Evidence suggests that multiple sclerosis is an immune disease. The literature also suggests that this disease may respond to immunosuppressants.1 In preparation for a multicenter clinical trial of the safety and efficacy of cyclosporine in the treatment of multiple sclerosis, we obtained serum samples from patients with definite2 chronic progressive multiple sclerosis (i.e., it had worsened over the previous year by at least 1.0, but no more than 3.0, units on the expanded disability status scale)3; from patients matched for disability who had multiple sclerosis that had been stable for one year; from normal control subjects;.
AB - To the Editor: Evidence suggests that multiple sclerosis is an immune disease. The literature also suggests that this disease may respond to immunosuppressants.1 In preparation for a multicenter clinical trial of the safety and efficacy of cyclosporine in the treatment of multiple sclerosis, we obtained serum samples from patients with definite2 chronic progressive multiple sclerosis (i.e., it had worsened over the previous year by at least 1.0, but no more than 3.0, units on the expanded disability status scale)3; from patients matched for disability who had multiple sclerosis that had been stable for one year; from normal control subjects;.
UR - http://www.scopus.com/inward/record.url?scp=0024278498&partnerID=8YFLogxK
U2 - 10.1056/NEJM198805053181816
DO - 10.1056/NEJM198805053181816
M3 - Letter
C2 - 3258957
AN - SCOPUS:0024278498
SN - 0028-4793
VL - 318
SP - 1206
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 18
ER -