Elevated Serum Interleukin-2 Levels in Chronic Progressive Multiple Sclerosis

John L. Trotter, David B. Clifford, Charles B. Anderson, Roel C. Van Der Veen, Byron C. Hicks, Geneva Banks

Research output: Contribution to journalLetterpeer-review

5 Scopus citations


To the Editor: Evidence suggests that multiple sclerosis is an immune disease. The literature also suggests that this disease may respond to immunosuppressants.1 In preparation for a multicenter clinical trial of the safety and efficacy of cyclosporine in the treatment of multiple sclerosis, we obtained serum samples from patients with definite2 chronic progressive multiple sclerosis (i.e., it had worsened over the previous year by at least 1.0, but no more than 3.0, units on the expanded disability status scale)3; from patients matched for disability who had multiple sclerosis that had been stable for one year; from normal control subjects;.

Original languageEnglish
Number of pages1
JournalNew England Journal of Medicine
Issue number18
StatePublished - May 5 1988


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