Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy

Mohammad Alyamani; Patrick Michael; Daniel Hettel; Lewis Thomas; Scott D. Lundy; Mike Berk; Mona Patel; Jianbo Li; Hooman Rashidi; Jesse K. McKenney; Eric A. Klein; Nima Sharifi

doi:10.1172/JCI171117

Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy

Mohammad Alyamani
, Patrick Michael
, Daniel Hettel
, Lewis Thomas
, Scott D. Lundy
, Mike Berk
, Mona Patel
, Jianbo Li
, Hooman Rashidi
, Jesse K. McKenney
, Eric A. Klein
, Nima Sharifi

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

These data suggest that a large proportion of men have a previously unappreciated exposure to an undiluted and highly concentrated T supply. Elevated periprostatic T exposure was associated with worse clinical outcomes after radical prostatectomy.

Original language	English
Article number	e171117
Journal	Journal of Clinical Investigation
Volume	133
Issue number	17
DOIs	https://doi.org/10.1172/JCI171117
State	Published - Sep 1 2023

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Alyamani, M., Michael, P., Hettel, D., Thomas, L., Lundy, S. D., Berk, M., Patel, M., Li, J., Rashidi, H., McKenney, J. K., Klein, E. A., & Sharifi, N. (2023). Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy. Journal of Clinical Investigation, 133(17), Article e171117. https://doi.org/10.1172/JCI171117

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title = "Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy",

abstract = "These data suggest that a large proportion of men have a previously unappreciated exposure to an undiluted and highly concentrated T supply. Elevated periprostatic T exposure was associated with worse clinical outcomes after radical prostatectomy.",

author = "Mohammad Alyamani and Patrick Michael and Daniel Hettel and Lewis Thomas and Lundy, \{Scott D.\} and Mike Berk and Mona Patel and Jianbo Li and Hooman Rashidi and McKenney, \{Jesse K.\} and Klein, \{Eric A.\} and Nima Sharifi",

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year = "2023",

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doi = "10.1172/JCI171117",

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AU - Alyamani, Mohammad

AU - Michael, Patrick

AU - Hettel, Daniel

AU - Thomas, Lewis

AU - Lundy, Scott D.

AU - Berk, Mike

AU - Patel, Mona

AU - Li, Jianbo

AU - Rashidi, Hooman

AU - McKenney, Jesse K.

AU - Klein, Eric A.

AU - Sharifi, Nima

PY - 2023/9/1

Y1 - 2023/9/1

N2 - These data suggest that a large proportion of men have a previously unappreciated exposure to an undiluted and highly concentrated T supply. Elevated periprostatic T exposure was associated with worse clinical outcomes after radical prostatectomy.

AB - These data suggest that a large proportion of men have a previously unappreciated exposure to an undiluted and highly concentrated T supply. Elevated periprostatic T exposure was associated with worse clinical outcomes after radical prostatectomy.

UR - https://www.scopus.com/pages/publications/85169397602

U2 - 10.1172/JCI171117

DO - 10.1172/JCI171117

M3 - Article

C2 - 37655657

AN - SCOPUS:85169397602

SN - 0021-9738

VL - 133

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 17

M1 - e171117

ER -

Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy

Abstract

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