Electrophysiological evidence for afferent nerve fibers in human ventral roots

Lawrence H. Phillips, T. S. Park, Mark E. Shaffrey, Christopher L. Shaffrey

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

This study was designed to test the hypothesis that ventral roots in humans contain afferent nerve fibers. We made direct electrophysiological recordings of compound nerve action potentials in dorsal and ventral roots in children undergoing selective dorsal rhizotomy for spastic cerebral palsy. We stimulated the saphenous or sural nerves, which are pure sensory nerves, with electrical stimuli while systematically recording from ventral and dorsal roots from L3 to S2. In addition to the dorsal root nerve action potentials which we expected, we found smaller compound nerve action potentials, which were clearly afferent, in the ventral roots. This confirms the limited amount of experimental evidence that ventral roots do contain some afferent nerve fibers. The functional significance of these observations is not yet clear. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish
Pages (from-to)410-415
Number of pages6
JournalMuscle and Nerve
Volume23
Issue number3
DOIs
StatePublished - Mar 13 2000

Keywords

  • Dorsal roots
  • Law of Belt and Magendie
  • Neuroanatomy
  • Ventral root afferents

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