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Elastin in lung development and disease pathogenesis
Robert P. Mecham
Department of Cell Biology & Physiology
Center for the Investigation of Membrane Excitability Diseases
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Center of Regenerative Medicine
DBBS - Molecular Cell Biology
DBBS - Developmental, Regenerative and Stem Cell Biology
Research output
:
Contribution to journal
›
Review article
›
peer-review
129
Scopus citations
Overview
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Keyphrases
Elastin
100%
Disease Pathogenesis
100%
Lung Disease
100%
Lung Development
100%
Elastic Fibers
50%
Lung
33%
Airway
16%
Vertebrates
16%
Endothelial Cells
16%
Extracellular Matrix
16%
Fibroblasts
16%
Multiple Cell Types
16%
Smooth muscle Cells
16%
Highly Crosslinked
16%
Fiber Fabrication
16%
Fibrillin-1 (FBN1)
16%
Microfibrils
16%
Bronchi
16%
Vasculature
16%
Elastic Recoil
16%
Pleura
16%
Blood Vessels
16%
Pulmonary Artery
16%
Lung Dysfunction
16%
Protein Cross-linking
16%
Applied Force
16%
Mesothelial Cells
16%
Cable
16%
Circulatory System
16%
Normal Lung Function
16%
Fiber Degradation
16%
Lamellae
16%
Elastin Fibers
16%
Terminal Airspace
16%
Alveolar Duct
16%
Evolutionary Success
16%
Distal Airspaces
16%
Smooth muscle Layer
16%
Fiber Network
16%
Visceral Pleura
16%
Physiological Structure
16%
Medicine and Dentistry
Elastin
100%
Lung Development
100%
Diseases
100%
Lung
57%
Elastic Fiber
42%
Visceral Pleura
28%
Secretion (Process)
14%
Extracellular Matrix
14%
Endothelial Cell
14%
Vascularity
14%
Smooth Muscle Cell
14%
Smooth Muscle
14%
Vascular Bundle
14%
Fibrillin
14%
Elastic Recoil
14%
Mesothelial Cell
14%
Circulatory System
14%
Fibroblast
14%
Evolution
14%
Engineering
Dysfunction
100%
Applied Force
100%
Microfibril
100%
Duct
100%
Multiple Cell Type
100%
Air Space
100%
Immunology and Microbiology
Elastic Fiber
100%
Lung Development
100%
Pleurae
66%
Secretion (Process)
33%
Extracellular Matrix
33%
Vascularization
33%
Lineages
33%
Smooth Muscle Cell
33%
Blood Vessels
33%
Smooth Muscle
33%
Fibroblast
33%
Evolution
33%
Airway
33%
Biochemistry, Genetics and Molecular Biology
Lung Development
100%
Elastin
100%
Elastic Fiber
42%
Secretion (Process)
14%
Vascularization
14%
Fibrillin
14%
Fibroblast
14%
Evolution
14%