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Efficient synthesis, liquid chromatography purification, and tandem mass spectrometric characterization of estrogen-modified DNA bases
Qiang Zhang
,
Michael L. Gross
Institute of Clinical and Translational Sciences
Division of Endocrinology, Metabolism & Lipid Research
Department of Chemistry
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Biochemistry, Biophysics, and Structural Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
8
Scopus citations
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Chemical Compounds
Purine
88%
Estrone
71%
Liquid Chromatography
64%
Estrogen
62%
Purification
59%
Quinone
55%
Steroid
53%
4-Hydroxyestrone
53%
Fragmentation
48%
Tandem Mass Spectrum
39%
Estradiol
33%
Oxidant Agent
33%
Modification
32%
Michael Addition
30%
Catechol
29%
Adenosine
27%
Biological Marker
26%
Dehydration
24%
Tandem Mass Spectrometry
24%
Adduct
20%
Dioxygen
14%
Ion
11%
Acid
10%
Medicine & Life Sciences
hydroxide ion
100%
Liquid Chromatography
91%
Estrogens
72%
DNA
48%
4-hydroxyestrone
37%
Quinones
28%
Purines
26%
Estrone
24%
o-iodoxybenzoic acid
23%
4-hydroxyestradiol
17%
Catechol Estrogens
15%
Steroids
14%
Ketones
12%
DNA Adducts
12%
purine
11%
Adenosine Monophosphate
10%
Isotopes
10%
Dehydration
10%
Oxidants
10%
Estradiol
8%
Ions
8%
Oxygen
6%
Biomarkers
6%
Neoplasms
3%