Abstract
Background: Endoscopic mucosal resection (EMR) for small (< 20 mm) duodenal neuroendocrine tumors (NETs) remains controversial because of their rarity. Materials and Methods: This is a retrospective cohort study of patients with surgically or endoscopically resected duodenal NETs from 2001 to 2011. The primary outcome is the rate of disease-free status following resection. A secondary outcome is the sensitivity of endoscopic ultrasound (EUS) in determining NET appropriateness for EMR. Results: Thirty patients underwent resection of duodenal NETs (EMR 20, surgery 10). Tumor was present at the margins in 40% of EMR-resected NETs and 10% of surgically resected NETs. Five patients who underwent EMR had residual disease treated with repeat EMR (3) and surgery (2). EUS demonstrated 96% sensitivity in determining lesions limited to the submucosa. Conclusions: EMR for small duodenal NETs can be a safe and effective alternative to surgery in carefully selected patients. EUS is a useful adjunct in determining depth of invasion for duodenal NETs.
Original language | English |
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Pages (from-to) | e134-e139 |
Journal | Surgical Laparoscopy, Endoscopy and Percutaneous Techniques |
Volume | 25 |
Issue number | 5 |
DOIs | |
State | Published - Nov 11 2015 |
Keywords
- Carcinoid
- Duodenum
- EMR
- EUS
- Neuroendocrine
- Tumor