TY - JOUR
T1 - Effects of varying case definition on carpal tunnel syndrome prevalence estimates in a pooled cohort
AU - Thiese, Matthew S.
AU - Gerr, Fred
AU - Hegmann, Kurt T.
AU - Harris-Adamson, Carisa
AU - Dale, Ann Marie
AU - Evanoff, Bradley
AU - Eisen, Ellen A.
AU - Kapellusch, Jay
AU - Garg, Arun
AU - Burt, Susan
AU - Bao, Stephen
AU - Silverstein, Barbara
AU - Merlino, Linda
AU - Rempel, David
N1 - Publisher Copyright:
© 2014 by the American Congress of Rehabilitation Medicine.
PY - 2014
Y1 - 2014
N2 - Objective: To analyze differences in carpal tunnel syndrome (CTS) prevalence using a combination of electrodiagnostic studies (EDSs) and symptoms using EDS criteria varied across a range of cutpoints and compared with symptoms in both ≥1 and ≥2 median nerveeserved digits. Design: Pooled data from 5 prospective cohorts. Setting: Hand-intensive industrial settings, including manufacturing, assembly, production, service, construction, and health care. Participants: Employed, working-age participants who are able to provide consent and undergo EDS testing (N=3130). Interventions: None. Main Outcome Measures: CTS prevalence was estimated while varying the thresholds for median sensory latency, median motor latency, and transcarpal delta latency difference. EDS criteria examined included the following: median sensory latency of 3.3 to 4.1 milliseconds, median motor latency of 4.1 to 4.9 milliseconds, and median-ulnar sensory difference of 0.4 to 1.2 milliseconds. EDS criteria were combined with symptoms in ≥1 or ≥2 median nerve-served digits. EDS criteria from other published studies were applied to allow for comparison. Results: CTS prevalence ranged from 6.3% to 11.7%. CTS prevalence estimates changed most per millisecond of sensory latency compared with motor latency or transcarpal delta. CTS prevalence decreased by 0.9% to 2.0% if the criteria required symptoms in 2 digits instead of 1. Conclusions: There are meaningful differences in CTS prevalence when different EDS criteria are applied. The digital sensory latency criteria result in the largest variance in prevalence.
AB - Objective: To analyze differences in carpal tunnel syndrome (CTS) prevalence using a combination of electrodiagnostic studies (EDSs) and symptoms using EDS criteria varied across a range of cutpoints and compared with symptoms in both ≥1 and ≥2 median nerveeserved digits. Design: Pooled data from 5 prospective cohorts. Setting: Hand-intensive industrial settings, including manufacturing, assembly, production, service, construction, and health care. Participants: Employed, working-age participants who are able to provide consent and undergo EDS testing (N=3130). Interventions: None. Main Outcome Measures: CTS prevalence was estimated while varying the thresholds for median sensory latency, median motor latency, and transcarpal delta latency difference. EDS criteria examined included the following: median sensory latency of 3.3 to 4.1 milliseconds, median motor latency of 4.1 to 4.9 milliseconds, and median-ulnar sensory difference of 0.4 to 1.2 milliseconds. EDS criteria were combined with symptoms in ≥1 or ≥2 median nerve-served digits. EDS criteria from other published studies were applied to allow for comparison. Results: CTS prevalence ranged from 6.3% to 11.7%. CTS prevalence estimates changed most per millisecond of sensory latency compared with motor latency or transcarpal delta. CTS prevalence decreased by 0.9% to 2.0% if the criteria required symptoms in 2 digits instead of 1. Conclusions: There are meaningful differences in CTS prevalence when different EDS criteria are applied. The digital sensory latency criteria result in the largest variance in prevalence.
KW - Carpal tunnel syndrome
KW - Diagnostic techniques and procedures
KW - Electrodiagnosis
KW - Prevalence
KW - Rehabilitation
KW - Standards
UR - http://www.scopus.com/inward/record.url?scp=84927909509&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2014.08.004
DO - 10.1016/j.apmr.2014.08.004
M3 - Article
C2 - 25175160
AN - SCOPUS:84927909509
SN - 0003-9993
VL - 95
SP - 2320
EP - 2326
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 12
ER -