Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view

M. R. Holland; U. M. Wilenshoff; A. F.F. Johnston; S. M. Handley; J. E. Perez; J. G. Miller

doi:10.1016/S0894-7317(98)70134-8

Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view

M. R. Holland, U. M. Wilenshoff, A. F.F. Johnston, S. M. Handley, J. E. Perez, J. G. Miller

Division of Cardiology

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

We measured the regional disparity in backscattered ultrasound by means of obtaining integrated backscatter images of 10 healthy subjects and placing a region of interest in 18 distinct positions. A computer model simulating the short-axis view was implemented on the basis of previously measured values for the anisotropic ultrasonic properties of myocardium. Measurements showed that the integrated backscatter value was greatest for the anterior septum and decreased by 15.9 ± 3.5 dB for the lateral wall and 17.7 ± 3.5 dB for the inferior septum. The value in the posterior wall was 8.1 ± 3.8 dB below the value for the anterior septum. The regional variation of backscatter predicted with the simulation correlated well with the clinical measurements. These results suggested that analyses based on measurements of backscatter may require compensation for the inherent anisotropic properties of myocardium.

Original language	English
Pages (from-to)	929-937
Number of pages	9
Journal	Journal of the American Society of Echocardiography
Volume	11
Issue number	10
DOIs	https://doi.org/10.1016/S0894-7317(98)70134-8
State	Published - 1998

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10.1016/S0894-7317(98)70134-8

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Holland, M. R., Wilenshoff, U. M., Johnston, A. F. F., Handley, S. M., Perez, J. E., & Miller, J. G. (1998). Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view. Journal of the American Society of Echocardiography, 11(10), 929-937. https://doi.org/10.1016/S0894-7317(98)70134-8

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title = "Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view",

abstract = "We measured the regional disparity in backscattered ultrasound by means of obtaining integrated backscatter images of 10 healthy subjects and placing a region of interest in 18 distinct positions. A computer model simulating the short-axis view was implemented on the basis of previously measured values for the anisotropic ultrasonic properties of myocardium. Measurements showed that the integrated backscatter value was greatest for the anterior septum and decreased by 15.9 ± 3.5 dB for the lateral wall and 17.7 ± 3.5 dB for the inferior septum. The value in the posterior wall was 8.1 ± 3.8 dB below the value for the anterior septum. The regional variation of backscatter predicted with the simulation correlated well with the clinical measurements. These results suggested that analyses based on measurements of backscatter may require compensation for the inherent anisotropic properties of myocardium.",

author = "Holland, {M. R.} and Wilenshoff, {U. M.} and Johnston, {A. F.F.} and Handley, {S. M.} and Perez, {J. E.} and Miller, {J. G.}",

note = "Funding Information: Supported in part by NIH grants HL40302 and HL53461. ",

year = "1998",

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Holland, MR, Wilenshoff, UM, Johnston, AFF, Handley, SM, Perez, JE & Miller, JG 1998, 'Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view', Journal of the American Society of Echocardiography, vol. 11, no. 10, pp. 929-937. https://doi.org/10.1016/S0894-7317(98)70134-8

Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view. / Holland, M. R.; Wilenshoff, U. M.; Johnston, A. F.F. et al.
In: Journal of the American Society of Echocardiography, Vol. 11, No. 10, 1998, p. 929-937.

Research output: Contribution to journal › Article › peer-review

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T2 - Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view

AU - Holland, M. R.

AU - Wilenshoff, U. M.

AU - Johnston, A. F.F.

AU - Handley, S. M.

AU - Perez, J. E.

AU - Miller, J. G.

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AB - We measured the regional disparity in backscattered ultrasound by means of obtaining integrated backscatter images of 10 healthy subjects and placing a region of interest in 18 distinct positions. A computer model simulating the short-axis view was implemented on the basis of previously measured values for the anisotropic ultrasonic properties of myocardium. Measurements showed that the integrated backscatter value was greatest for the anterior septum and decreased by 15.9 ± 3.5 dB for the lateral wall and 17.7 ± 3.5 dB for the inferior septum. The value in the posterior wall was 8.1 ± 3.8 dB below the value for the anterior septum. The regional variation of backscatter predicted with the simulation correlated well with the clinical measurements. These results suggested that analyses based on measurements of backscatter may require compensation for the inherent anisotropic properties of myocardium.

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Holland MR, Wilenshoff UM, Johnston AFF, Handley SM, Perez JE, Miller JG. Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view. Journal of the American Society of Echocardiography. 1998;11(10):929-937. doi: 10.1016/S0894-7317(98)70134-8

Effects of myocardial fiber orientation in echocardiography: Quantitative measurements and computer simulation of the regional dependence of backscattered ultrasound in the parasternal short-axis view

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