Effects of extracellular matrix mechanics on neuronal process extension

Lisa A. Flanagan, Yo El Ju, Paul A. Janmey

Research output: Contribution to journalConference article

2 Scopus citations

Abstract

The effects of extracellular matrix mechanics on neuronal process extension are studied. During development neurons extend numerous processes that differentiate into dendrites and axons. Results showed that polyacrylamide gels are useful substrates for determining effects of substrate deformability on cells as the stiffness of gels can be altered by changing the crosslinker concentration without any change in total polymer mass.

Original languageEnglish
Pages (from-to)379-380
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume50
StatePublished - Dec 1 2001
Externally publishedYes
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: Jun 27 2001Jul 1 2001

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