The effects of extracellular matrix mechanics on neuronal process extension are studied. During development neurons extend numerous processes that differentiate into dendrites and axons. Results showed that polyacrylamide gels are useful substrates for determining effects of substrate deformability on cells as the stiffness of gels can be altered by changing the crosslinker concentration without any change in total polymer mass.
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Bioengineering Division (Publication) BED|
|State||Published - Dec 1 2001|
|Event||Proceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States|
Duration: Jun 27 2001 → Jul 1 2001