Effects of exposure to noise on permeability to potassium of the endolymph-perilymph barrier in Guinea pigs

T. Konishi, A. N. Salt, P. E. Hamrick

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Healthy guinea pigs were exposed to broadband noise at 115 dBA for 7 days. When perfusion of the scala vestibuli was carried out with artificial perilymph containing 43K, the 43K concentrations in the perilymph of the scala tympani were very low in both control and noise-exposed guinea pigs. The transport rate constant for K+ was computed by utilizing compartmental analysis. The results indicate that exposure to noise at 115 dBA for 7 days does not alter the permeability to K+ of Reissner's membrane or the lateral wall of the cochlear duct but does decrease K+ conductance of the organ of Corti.

Original languageEnglish
Pages (from-to)395-401
Number of pages7
JournalActa Oto-Laryngologica
Volume94
Issue number1-6
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

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