Effects of endoplasmic reticulum stress on group VIA phospholipase A ₂in beta cells include tyrosine phosphorylation and increased association with calnexin

Keyphrases

• B Cells 100%
• Endoplasmic Reticulum Stress (ER stress) 100%
• Tyrosine Phosphorylation 100%
• IPLA2 100%
• Calnexin 100%
• Phospholipase A 100%
• Arachidonic Acid 16%
• Membrane Phospholipids 16%
• Phosphorylation 8%
• Overexpression 8%
• Apoptosis 8%
• Hydrolysis 8%
• Endoplasmic Reticulum 8%
• Free Fatty Acids 8%
• Insulin Secretion 8%
• Electrospray Ionization 8%
• Transcriptional Regulation 8%
• Interactome 8%
• Mitochondria 8%
• Stress-induced 8%
• Associated Proteins 8%
• Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) 8%
• Functional Significance 8%
• Phosphoprotein 8%
• Co-incubation 8%
• Regulatory Proteins 8%
• Fusion Protein 8%
• Insulinoma Cells 8%
• Sn-2 8%
• INS-1 8%
• Group VIA Phospholipase A2 8%
• INS-1 Cells 8%
• Acid Hydrolysis 8%
• Lysophospholipids 8%
• Trypsin 8%
• Database Search 8%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 8%
• MS-MS 8%
• Ca2+/calmodulin-dependent Protein Kinase II 8%
• Glycerophospholipids 8%
• Mouse Pancreatic Islets 8%
• Cell Lysis 8%
• Affinity Capture 8%
• Endoplasmic Reticulum Chaperones 8%
• Arterial Myocytes 8%
• Phospholipid Remodeling 8%
• Peptide Mixtures 8%
• SERCA Inhibitor 8%
• FLAG Peptide 8%

Biochemistry, Genetics and Molecular Biology

• Endoplasmic Reticulum Stress 100%
• Tyrosine Phosphorylation 100%
• Calnexin 100%
• Phospholipase A 100%
• Enzymatic Hydrolysis 60%
• Phospholipid 60%
• Tandem Mass Spectrometry 40%
• Arachidonic Acid 40%
• Interactome 20%
• Mitochondrion 20%
• Insulin Release 20%
• Polyacrylamide Gel Electrophoresis 20%
• Phosphoprotein 20%
• Phospholipase A2 20%
• Electrospray Ionization 20%
• Free Fatty Acids 20%
• Cytolysis 20%
• SERCA 20%
• Ca2+/Calmodulin-Dependent Protein Kinase II 20%
• Chimeric Protein 20%
• Glycerophospholipid 20%
• Programmed Cell Death 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Calcium Independent Phospholipase A2 100%
• Phospholipase A 100%
• Calnexin 100%
• Arachidonic Acid 16%
• Membrane Phospholipid 16%
• Fatty Acid 8%
• Phospholipid 8%
• Polyacrylamide Gel Electrophoresis 8%
• Phospholipase A2 8%
• Insulinoma 8%
• Electrospray Ionization 8%
• Regulator Protein 8%
• Calcium Calmodulin Dependent Protein Kinase 8%
• Phosphoprotein 8%
• Glycerophospholipid 8%
• Chimeric Protein 8%
• Lysophospholipid 8%