Effects of dietary glycyrrhizin on growth and nonspecific immunity of white shrimp, Litopenaeus vannamei

Xiaoru Chen, Kangsen Mai, Wenbing Zhang, Xiaojie Wang, Qinghui Ai, Wei Xu, Zhiguo Liufu, Hongming Ma, Beiping Tan

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The growth response, total hemocyte count (THC), respiratory burst (release of superoxide anion), phenoloxidase (PO) activity, superoxide dismutase (SOD) activity, nitric oxide synthase (NOS) activity as well as resistance to the pathogen Vibrio alginolyticus were measured in Litopenaeus vannamei, which had been fed diets supplemented with glycyrrhizin (the aqueous extract of licorice, Glycyrrhiza glabra, roots) at 0, 50, 100, 150, and 200 mg/kg of feed for 8 wk. In the feeding trial, there was no significant difference in survival rate (P >0.05). Significant higher specific growth rate was observed in treatments with dietary glycyrrhizin than that in the control group (P <0.05). Shrimp fed a diet with 200 mg/kg of glycyrrhizin had significant higher THC, PO activity, respiratory burst activity and SOD activity than that in the control group (P <0.05). Increased THC, respiratory burst activity and NOS activity were also noticed in shrimp fed glycyrrhizin at 100 or 150 mg/kg (P <0.05). There were significantly lower cumulative mortalities after the disease challenge in shrimp fed glycyrrhizin diets (8.33-16.67%) than that in the control group (36.67%) (P <0.05). These results indicated that glycyrrhizin may enhance the nonspecific immune system, increase the resistance of L. vannamei as well as improve production in shrimp farming.

Original languageEnglish
Pages (from-to)665-674
Number of pages10
JournalJournal of the World Aquaculture Society
Volume41
Issue number5
DOIs
StatePublished - Oct 1 2010
Externally publishedYes

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