Effects of azotemia on results of the boronate-agarose affinity and ion-exchange methods for glycated hemoglobin.

M. G. Scott, J. W. Hoffmann, V. N. Meltzer, B. A. Siegfried, K. M. Chan

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

We evaluated the effect of azotemia on results for glycated hemoglobin as measured by a boronate-agarose affinity method and an ion-exchange chromatographic procedure with saline preincubation and found a good correlation. However, values for glycated hemoglobin in samples from nondiabetic patients with various degrees of azotemia were consistently higher with the ion-exchange column procedure (mean, 8.5%) than with the boronate affinity method (mean, 6.2%). The latter method may thus be preferred for monitoring glycated hemoglobin in diabetic patients with impaired renal function.

Original languageEnglish
Pages (from-to)896-898
Number of pages3
JournalClinical chemistry
Volume30
Issue number6
DOIs
StatePublished - Jun 1984
Externally publishedYes

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