TY - JOUR
T1 - Effects of a household air pollution intervention with liquefied petroleum gas on cardiopulmonary outcomes in Peru. A randomized controlled trial
AU - CHAP Trial Investigators
AU - Checkley, William
AU - Williams, Kendra N.
AU - Kephart, Josiah L.
AU - Fandiño-Del-Rio, Magdalena
AU - Steenland, N. Kyle
AU - Gonzales, Gustavo F.
AU - Naeher, Luke P.
AU - Harvey, Steven A.
AU - Moulton, Lawrence H.
AU - Davila-Roman, Victor G.
AU - Goodman, Dina
AU - Tarazona-Meza, Carla
AU - Miele, Catherine H.
AU - Simkovich, Suzanne
AU - Chiang, Marilu
AU - Chartier, Ryan T.
AU - Koehler, Kirsten
AU - Rosenthal, Joshua
AU - Aguilar, Theresa
AU - Burrowes, Vanessa
AU - Fandiño-Del-Rio, Magdalena
AU - Fung, Elizabeth C.
AU - Goodman, Dina
AU - Harvey, Steven A.
AU - Herrera, Phabiola
AU - Kephart, Josiah L.
AU - Koehler, Kirsten
AU - Lee, Alexander
AU - Lee, Kathryn A.
AU - Miele, Catherine H.
AU - Moazzami, Mitra
AU - Moulton, Lawrence
AU - Nangia, Saachi
AU - Nicolaou, Laura
AU - O’Brien, Carolyn
AU - Simkovich, Suzanne
AU - Shade, Timothy
AU - Stashko, Lena
AU - Villegas-Gomez, Ariadne
AU - Williams, Kendra N.
AU - Winiker, Abigail
AU - Chiang, Marilu
AU - Malpartida, Gary
AU - Tarazona-Meza, Carla
AU - Davila-Roman, Victor
AU - de las Fuentes, Lisa
AU - Boyd, Dana Barr
AU - Jolly, Maria
AU - Rozo, Angela
N1 - Publisher Copyright:
Copyright © 2021 by the American Thoracic Society
PY - 2021/6/1
Y1 - 2021/6/1
N2 - Rationale: Approximately 40% of people worldwide are exposed to household air pollution (HAP) from the burning of biomass fuels. Previous efforts to document health benefits of HAP mitigation have been stymied by an inability to lower emissions to target levels. Objectives: We sought to determine if a household air pollution intervention with liquefied petroleum gas (LPG) improved cardiopulmonary health outcomes in adult women living in a resource-poor setting in Peru. Methods: We conducted a randomized controlled field trial in 180 women aged 25–64 years living in rural Puno, Peru. Intervention women received an LPG stove, continuous fuel delivery for 1 year, education, and behavioral messaging, whereas control women were asked to continue their usual cooking practices. We assessed for stove use adherence using temperature loggers installed in both LPG and biomass stoves of intervention households. Measurements and Main Results: We measured blood pressure, peak expiratory flow (PEF), and respiratory symptoms using the St. George’s Respiratory Questionnaire at baseline and at 3–4 visits after randomization. Intervention women used their LPG stove exclusively for 98% of days. We did not find differences in average postrandomization systolic blood pressure (intervention – control 0.7 mm Hg; 95% confidence interval, 22.1 to 3.4), diastolic blood pressure (0.3 mm Hg; 21.5 to 2.0), prebronchodilator peak expiratory flow/height2 (0.14 L/s/m2; 20.02 to 0.29), postbronchodilator peak expiratory flow/height2 (0.11 L/s/m2; 20.05 to 0.27), or St. George’s Respiratory Questionnaire total score (21.4; 23.9 to 1.2) over 1 year in intention-to-treat analysis. There were no reported harms related to the intervention. Conclusions: We did not find evidence of a difference in blood pressure, lung function, or respiratory symptoms during the year-long intervention with LPG.
AB - Rationale: Approximately 40% of people worldwide are exposed to household air pollution (HAP) from the burning of biomass fuels. Previous efforts to document health benefits of HAP mitigation have been stymied by an inability to lower emissions to target levels. Objectives: We sought to determine if a household air pollution intervention with liquefied petroleum gas (LPG) improved cardiopulmonary health outcomes in adult women living in a resource-poor setting in Peru. Methods: We conducted a randomized controlled field trial in 180 women aged 25–64 years living in rural Puno, Peru. Intervention women received an LPG stove, continuous fuel delivery for 1 year, education, and behavioral messaging, whereas control women were asked to continue their usual cooking practices. We assessed for stove use adherence using temperature loggers installed in both LPG and biomass stoves of intervention households. Measurements and Main Results: We measured blood pressure, peak expiratory flow (PEF), and respiratory symptoms using the St. George’s Respiratory Questionnaire at baseline and at 3–4 visits after randomization. Intervention women used their LPG stove exclusively for 98% of days. We did not find differences in average postrandomization systolic blood pressure (intervention – control 0.7 mm Hg; 95% confidence interval, 22.1 to 3.4), diastolic blood pressure (0.3 mm Hg; 21.5 to 2.0), prebronchodilator peak expiratory flow/height2 (0.14 L/s/m2; 20.02 to 0.29), postbronchodilator peak expiratory flow/height2 (0.11 L/s/m2; 20.05 to 0.27), or St. George’s Respiratory Questionnaire total score (21.4; 23.9 to 1.2) over 1 year in intention-to-treat analysis. There were no reported harms related to the intervention. Conclusions: We did not find evidence of a difference in blood pressure, lung function, or respiratory symptoms during the year-long intervention with LPG.
KW - Blood pressure
KW - Household air pollution
KW - Lung function
KW - Respiratory symptoms
UR - http://www.scopus.com/inward/record.url?scp=85105581818&partnerID=8YFLogxK
U2 - 10.1164/rccm.202006-2319OC
DO - 10.1164/rccm.202006-2319OC
M3 - Article
C2 - 33306939
AN - SCOPUS:85105581818
SN - 1073-449X
VL - 203
SP - 1386
EP - 1397
JO - American journal of respiratory and critical care medicine
JF - American journal of respiratory and critical care medicine
IS - 11
ER -