Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship during a Drug Shortage

Kevin Hsueh; Maria Reyes; Tamara Krekel; Ed Casabar; David J. Ritchie; S. Reza Jafarzadeh; Amanda J. Hays; Michael A. Lane; Michael J. Durkin

doi:10.1017/ice.2016.289

Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship during a Drug Shortage

Kevin Hsueh
, Maria Reyes
, Tamara Krekel
, Ed Casabar
, David J. Ritchie
, S. Reza Jafarzadeh
, Amanda J. Hays
, Michael A. Lane
, Michael J. Durkin

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged.

Original language	English
Pages (from-to)	356-359
Number of pages	4
Journal	Infection Control and Hospital Epidemiology
Volume	38
Issue number	3
DOIs	https://doi.org/10.1017/ice.2016.289
State	Published - Mar 1 2017

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10.1017/ice.2016.289

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abstract = "We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69\% and piperacillin-tazobactam by 73\%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged.",

author = "Kevin Hsueh and Maria Reyes and Tamara Krekel and Ed Casabar and Ritchie, \{David J.\} and Jafarzadeh, \{S. Reza\} and Hays, \{Amanda J.\} and Lane, \{Michael A.\} and Durkin, \{Michael J.\}",

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AU - Jafarzadeh, S. Reza

AU - Hays, Amanda J.

AU - Lane, Michael A.

AU - Durkin, Michael J.

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AB - We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged.

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Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship during a Drug Shortage

Abstract

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