Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship during a Drug Shortage

Kevin Hsueh, Maria Reyes, Tamara Krekel, Ed Casabar, David J. Ritchie, S. Reza Jafarzadeh, Amanda J. Hays, Michael A. Lane, Michael J. Durkin

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged.

Original languageEnglish
Pages (from-to)356-359
Number of pages4
JournalInfection Control and Hospital Epidemiology
Volume38
Issue number3
DOIs
StatePublished - Mar 1 2017

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