Effect of reorientation on myocardial blood flow estimation from dynamic 13NH3 PET imaging

Xiao Bo Pan, Thomas H. Schindler, Osman Ratib, Stephan Nekolla, Jerome Declerck

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

This paper describes a study of assessing the effect of reorientation variation on the myocardial blood flow (MBF) estimation from dynamic PET cardiac acquisition using 13NH3. 58 13NH3 dynamic datasets were reoriented with an automatic algorithm. For each dataset a series of 20 random reorientations were generated from the automatically computed result. The variation of MBF with the reorientation parameters was assessed using the coefficient of variation (CV). The mean, standard deviation and max of CV for the 58 datasets with reorientation and center perturbation are computed for the three AHA vessel regions: LAD (4.8%, 3.3%, 21.1%), LCX (4.5%, 3.3%, 20.3%), RCA (5.6%, 5.4%, 30.6%), all regions combined (4.5%, 3.3%, 17.1%). The results show manual adjustment of the reorientation is not expected to cause large variation on the MBF estimation on the three vessel regions or globally, if the placement of the BIF ROI is appropriate.

Original languageEnglish
Title of host publication2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Pages3715-3716
Number of pages2
DOIs
StatePublished - Dec 1 2009
Event2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States
Duration: Oct 25 2009Oct 31 2009

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Country/TerritoryUnited States
CityOrlando, FL
Period10/25/0910/31/09

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