TY - JOUR
T1 - Effect of ethanol on formation of bile
AU - Strasberg, S. M.
PY - 1981
Y1 - 1981
N2 - The effects of ethanol on bile formation have been studied in the rat, dog, and man, in both acute and chronic models. The acute and chronic effects differ. Given acutely, ethanol suppresses bile flow and bile acid secretion rate. Chronic administration appears to increase both components of canalicular flow and bile acid secretion rate. Intestinal and hepatic actions are probably involved in the latter effect, Secretion of other biliary lipids and diagnostic anions are also reduced by ethanol.
AB - The effects of ethanol on bile formation have been studied in the rat, dog, and man, in both acute and chronic models. The acute and chronic effects differ. Given acutely, ethanol suppresses bile flow and bile acid secretion rate. Chronic administration appears to increase both components of canalicular flow and bile acid secretion rate. Intestinal and hepatic actions are probably involved in the latter effect, Secretion of other biliary lipids and diagnostic anions are also reduced by ethanol.
UR - http://www.scopus.com/inward/record.url?scp=0019801448&partnerID=8YFLogxK
U2 - 10.1111/j.1530-0277.1981.tb04874.x
DO - 10.1111/j.1530-0277.1981.tb04874.x
M3 - Review article
C2 - 7013537
AN - SCOPUS:0019801448
SN - 0145-6008
VL - 5
SP - 119
EP - 124
JO - Alcoholism: Clinical and Experimental Research
JF - Alcoholism: Clinical and Experimental Research
IS - 1
ER -