Effect of dietary vitamin C and β-glucan on immunity and disease resistance of Japanese flounder (Paralichthys olivaceus)

Zhengli Wang, Kangsen Mai, Zhiguo Liufu, Qinghui Ai, Wei Xu, Hongming Ma, Wenbing Zhang, Beiping Tan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A feeding experiment was conducted to investigate the effects of dietary vitamin C (supplied as L-ascorbyl-2-polyphosphate) and β-glucan on the non-specific immune response and disease resistance of Japanese flounder (initial body weight: 40.5 ± 1.0 g) in a re-circulation system. The results showed that dietary vitamin C had a significant positive effect on ACH50 when the fish were fed with diet without β-glucan. However, dietary vitamin C had no significant effect on lysozyme activity, respiratory burst activity, and disease resistance to E. tarda (P > 0.05). The serum ACH50 significantly increased with the increase of dietary p-glucan when feeding the vitamin C-deficiency diet. In the groups with 1.0 mg kg-1 vitamin C, ACH50 significantly increased with the increase of dietary glucan (P < 0.05). The fish fed with glucan-deficiency diets had significantly lower respiratory burst activity (P < 0.05) when being fed with the diets with 1.0 and 495.0 mg ascorbic acid kg-1 diet (P < 0.05). The fish fed with glucan-deficiency diets had significantly higher cumulative mortality than those fed with diets supplemented with 0.6% glucan after 7 days following E. tarda exposure in the presence of dietary vitamin C.

Original languageEnglish
Pages (from-to)757-762
Number of pages6
JournalGaojishu Tongxin/Chinese High Technology Letters
Volume16
Issue number7
StatePublished - Jul 1 2006

Keywords

  • Disease resistance
  • Immunity
  • Japanese flounder
  • Vitamin C
  • β-glucan

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