TY - GEN
T1 - Effect of alternative diastolic pressure-volume relations on transmitral Doppler flow
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
AU - Lisauskas, Jennifer B.
AU - Kovacs, Sandor J.
PY - 1999
Y1 - 1999
N2 - Several mathematical expressions (linear, exponential, logarithmic) have been used to fit the measured diastolic pressure-volume (P-V) relation. We determined whether the different P-V relations could be distinguished by analysis of in-vivo physiologic data. Transmitral Doppler E-waves of 15 subjects were analyzed using model-based image processing (MBIP). One dimensional linear, logarithmic, and exponential force displacement equivalents of the P-V relation were used in our lumped-parameter kinematic model of transmitral flow for MBIP. Minimized least-square best fits of model predicted to observed Doppler E-wave flow velocity were similar regardless of choice of mathematical expression. We conclude that application of the simplest P-V relation is justified in MBIP analysis of transmitral Doppler flow.
AB - Several mathematical expressions (linear, exponential, logarithmic) have been used to fit the measured diastolic pressure-volume (P-V) relation. We determined whether the different P-V relations could be distinguished by analysis of in-vivo physiologic data. Transmitral Doppler E-waves of 15 subjects were analyzed using model-based image processing (MBIP). One dimensional linear, logarithmic, and exponential force displacement equivalents of the P-V relation were used in our lumped-parameter kinematic model of transmitral flow for MBIP. Minimized least-square best fits of model predicted to observed Doppler E-wave flow velocity were similar regardless of choice of mathematical expression. We conclude that application of the simplest P-V relation is justified in MBIP analysis of transmitral Doppler flow.
UR - http://www.scopus.com/inward/record.url?scp=0033340732&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033340732
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 220
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
Y2 - 13 October 1999 through 16 October 1999
ER -