TY - JOUR
T1 - Economic burden of antibiotic resistance
T2 - How much do we really know?
AU - Gandra, S.
AU - Barter, D. M.
AU - Laxminarayan, R.
N1 - Funding Information:
We would like to thank N. Bornkamp, Department of Ecology and Evolutionary Biology, Princeton University, for research assistance. Any errors that remain are the responsibility of the authors. This research was supported by the Science and Technology Directorate, Department of Homeland Security contract HSHQDC-12-C-00058, and the Global Antibiotic Resistance Partnership, funded by the Bill & Melinda Gates Foundation.
Publisher Copyright:
© 2014 European Society of Clinical Microbiology and Infectious Diseases.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - The declining effectiveness of antibiotics imposes potentially large health and economic burdens on societies. Quantifying the economic outcomes of antibiotic resistance effectively can help policy-makers and healthcare professionals to set priorities, but determining the actual effect of antibiotic resistance on clinical outcomes is a necessary first step. In this article, we review and discuss the contributions and limitations of studies that estimate the disease burden attributable to antibiotic resistance and studies that estimate the economic burden of resistance. We also consider other factors that are important in a comprehensive approach to evaluating the economic burden of antibiotic resistance.
AB - The declining effectiveness of antibiotics imposes potentially large health and economic burdens on societies. Quantifying the economic outcomes of antibiotic resistance effectively can help policy-makers and healthcare professionals to set priorities, but determining the actual effect of antibiotic resistance on clinical outcomes is a necessary first step. In this article, we review and discuss the contributions and limitations of studies that estimate the disease burden attributable to antibiotic resistance and studies that estimate the economic burden of resistance. We also consider other factors that are important in a comprehensive approach to evaluating the economic burden of antibiotic resistance.
KW - Antibiotic resistance
KW - Attributable morbidity and mortality
KW - Economics
UR - http://www.scopus.com/inward/record.url?scp=84912531425&partnerID=8YFLogxK
U2 - 10.1111/1469-0691.12798
DO - 10.1111/1469-0691.12798
M3 - Review article
C2 - 25273968
AN - SCOPUS:84912531425
SN - 1198-743X
VL - 20
SP - 973
EP - 979
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
IS - 10
ER -