Ebola Virus Replication Stands Out

Wenjie Wang; Chao Wu; Gaya K. Amarasinghe; Daisy W. Leung

doi:10.1016/j.tim.2019.05.004

Ebola Virus Replication Stands Out

Wenjie Wang
, Chao Wu
, Gaya K. Amarasinghe
, Daisy W. Leung

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535–8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.

Original language	English
Pages (from-to)	565-566
Number of pages	2
Journal	Trends in Microbiology
Volume	27
Issue number	7
DOIs	https://doi.org/10.1016/j.tim.2019.05.004
State	Published - Jul 2019

Keywords

Ebola virus
innate immune evasion
replication initiation

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10.1016/j.tim.2019.05.004

Cite this

@article{4360b52bf1d64480b9817e3740196f29,

title = "Ebola Virus Replication Stands Out",

abstract = "A recent study by Deflub{\'e} et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535{\textendash}8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.",

keywords = "Ebola virus, innate immune evasion, replication initiation",

author = "Wenjie Wang and Chao Wu and Amarasinghe, \{Gaya K.\} and Leung, \{Daisy W.\}",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = jul,

doi = "10.1016/j.tim.2019.05.004",

language = "English",

volume = "27",

pages = "565--566",

journal = "Trends in Microbiology",

issn = "0966-842X",

number = "7",

}

TY - JOUR

T1 - Ebola Virus Replication Stands Out

AU - Wang, Wenjie

AU - Wu, Chao

AU - Amarasinghe, Gaya K.

AU - Leung, Daisy W.

PY - 2019/7

Y1 - 2019/7

N2 - A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535–8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.

AB - A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535–8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.

KW - Ebola virus

KW - innate immune evasion

KW - replication initiation

UR - https://www.scopus.com/pages/publications/85066283295

U2 - 10.1016/j.tim.2019.05.004

DO - 10.1016/j.tim.2019.05.004

M3 - Short survey

C2 - 31155428

AN - SCOPUS:85066283295

SN - 0966-842X

VL - 27

SP - 565

EP - 566

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 7

ER -

Ebola Virus Replication Stands Out

Abstract

Keywords

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