TY - JOUR
T1 - Ebola Virus Replication Stands Out
AU - Wang, Wenjie
AU - Wu, Chao
AU - Amarasinghe, Gaya K.
AU - Leung, Daisy W.
N1 - Publisher Copyright:
© 2019
PY - 2019/7
Y1 - 2019/7
N2 - A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535–8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.
AB - A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535–8543) reported that Ebola virus genomes have variable 3′ terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.
KW - Ebola virus
KW - innate immune evasion
KW - replication initiation
UR - http://www.scopus.com/inward/record.url?scp=85066283295&partnerID=8YFLogxK
U2 - 10.1016/j.tim.2019.05.004
DO - 10.1016/j.tim.2019.05.004
M3 - Short survey
C2 - 31155428
AN - SCOPUS:85066283295
SN - 0966-842X
VL - 27
SP - 565
EP - 566
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 7
ER -