TY - JOUR
T1 - Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging
AU - Ren, Chao
AU - Hao, Senyue
AU - Wang, Fei
AU - Matt, Abigail
AU - Amaral, Marcello Magri
AU - Yang, Daniel
AU - Wang, Leyao
AU - Zhou, Chao
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/12
Y1 - 2024/12
N2 - Dynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non-invasive label-free volumetric live cell imaging. In this mini review, we explain the core concepts behind DyC-OCT image formation and its system configurations, serving as practical guidance for future DyC-OCT users. Subsequently, we explore its applications in delivering high-quality, contrast-enhanced images of cellular morphology, as well as in monitoring changes in cellular activity/viability assay experiments.
AB - Dynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non-invasive label-free volumetric live cell imaging. In this mini review, we explain the core concepts behind DyC-OCT image formation and its system configurations, serving as practical guidance for future DyC-OCT users. Subsequently, we explore its applications in delivering high-quality, contrast-enhanced images of cellular morphology, as well as in monitoring changes in cellular activity/viability assay experiments.
UR - http://www.scopus.com/inward/record.url?scp=85187164968&partnerID=8YFLogxK
U2 - 10.1038/s42003-024-05973-5
DO - 10.1038/s42003-024-05973-5
M3 - Short survey
C2 - 38448627
AN - SCOPUS:85187164968
SN - 2399-3642
VL - 7
JO - Communications Biology
JF - Communications Biology
IS - 1
M1 - 278
ER -