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Keyphrases
Hematological Malignancies
100%
Duvelisib
100%
Dual Inhibitor
100%
Phosphoinositide 3-kinase (PI3K)
100%
Twice Daily
42%
Chronic Lymphocytic Leukemia
42%
Complete Response
42%
Maximum Tolerated Dose
28%
Phase II Study
28%
Indolent non-Hodgkin Lymphoma
28%
Pneumonia
14%
Phase 1 Study
14%
Adverse Events
14%
Overall Response Rate
14%
Diarrhea
14%
Anemia
14%
Neutropenia
14%
Relapsed or Refractory
14%
Clinical Response
14%
Tumor Cells
14%
Expansion Process
14%
Dose Escalation
14%
Ki-67
14%
Median Time
14%
Thrombocytopenia
14%
T-cell Lymphoma
14%
Alanine Aminotransferase
14%
Aspartate Transaminase
14%
Near-complete
14%
Pharmacodynamics
14%
Peripheral T-cell Lymphoma
14%
Cutaneous T-cell Lymphoma
14%
Clinical Development
14%
Disease Subtypes
14%
Pharmacokinetics-pharmacodynamics (PK-PD)
14%
Phospho-Akt
14%
Time Response
14%
Chronic Lymphocytic Leukemia Cells
14%
Maximum Permissible Concentration
14%
Medicine and Dentistry
Phosphoinositide 3-Kinase
100%
Duvelisib
100%
Hematologic Malignancy
100%
Oral
100%
B-Cell Chronic Lymphocytic Leukemia
57%
Non-Hodgkin Lymphoma
28%
Single Drug Dose
28%
Pharmacodynamics
28%
Adverse Event
14%
Neutropenia
14%
Diarrhea
14%
Anemia
14%
Tumor Cell
14%
Clinical Stage
14%
Leukemia Cell
14%
Thrombocytopenia
14%
T-Cell Lymphoma
14%
Peripheral T-Cell Lymphoma
14%
Alanine Aminotransferase
14%
Aspartate Aminotransferase
14%
Cutaneous T Cell Lymphoma
14%
Pharmacokinetics
14%
Protein Kinase B
14%
Diseases
14%
Pharmacology, Toxicology and Pharmaceutical Science
Hematologic Malignancy
100%
Duvelisib
100%
Phosphatidylinositol 3 Kinase
100%
Chronic Lymphatic Leukemia
57%
Maximum Tolerated Dose
28%
Pharmacodynamics
28%
Nonhodgkin Lymphoma
28%
Neoplasm
14%
Anemia
14%
Diarrhea
14%
Neutropenia
14%
Adverse Event
14%
Thrombocytopenia
14%
Aspartate Aminotransferase
14%
Alanine Aminotransferase
14%
T Cell Lymphoma
14%
Peripheral T Cell Lymphoma
14%
Protein Kinase B
14%
Cutaneous T Cell Lymphoma
14%
Pharmacokinetics
14%
Diseases
14%