Dural marginal zone lymphoma in a patient with a hepatitis C virus infection

Matthew T. Villaume, Dilan Patel, Christine Lopez, Vivek Patel, Pauleatha Diggs, Hannah Harmsen, Mary Ann Thompson, David Morgan

Research output: Contribution to journalArticlepeer-review

Abstract

Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.

Original languageEnglish
Pages (from-to)122-125
Number of pages4
JournalWorld Journal of Oncology
Volume11
Issue number3
DOIs
StatePublished - Jun 1 2020

Keywords

  • Dura
  • Hepatitis C virus
  • Marginal zone lymphoma

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