Dural marginal zone lymphoma in a patient with a hepatitis C virus infection

Matthew T. Villaume; Dilan Patel; Christine Lopez; Vivek Patel; Pauleatha Diggs; Hannah Harmsen; Mary Ann Thompson; David Morgan

doi:10.14740/WJON1285

Dural marginal zone lymphoma in a patient with a hepatitis C virus infection

Matthew T. Villaume, Dilan Patel, Christine Lopez, Vivek Patel, Pauleatha Diggs, Hannah Harmsen, Mary Ann Thompson, David Morgan

Section of Medical Oncology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.

Original language	English
Pages (from-to)	122-125
Number of pages	4
Journal	World Journal of Oncology
Volume	11
Issue number	3
DOIs	https://doi.org/10.14740/WJON1285
State	Published - Jun 1 2020

Keywords

Dura
Hepatitis C virus
Marginal zone lymphoma

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10.14740/WJON1285

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title = "Dural marginal zone lymphoma in a patient with a hepatitis C virus infection",

abstract = "Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.",

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AU - Villaume, Matthew T.

AU - Patel, Dilan

AU - Lopez, Christine

AU - Patel, Vivek

AU - Diggs, Pauleatha

AU - Harmsen, Hannah

AU - Thompson, Mary Ann

AU - Morgan, David

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PY - 2020/6/1

Y1 - 2020/6/1

N2 - Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.

AB - Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.

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Dural marginal zone lymphoma in a patient with a hepatitis C virus infection

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