TY - JOUR
T1 - Dual-Organ Transplantation
T2 - Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation: A Scientific Statement from the American Heart Association
AU - Kittleson, Michelle M.
AU - Sharma, Kavita
AU - Brennan, Daniel C.
AU - Cheng, Xingxing S.
AU - Chow, Sheryl L.
AU - Colvin, Monica
AU - Devore, Adam D.
AU - Dunlay, Shannon M.
AU - Fraser, Meg
AU - Garonzik-Wang, Jacqueline
AU - Khazanie, Prateeti
AU - Korenblat, Kevin M.
AU - Pham, Duc T.
N1 - Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.
PY - 2023/8/15
Y1 - 2023/8/15
N2 - Although heart transplantation is the preferred therapy for appropriate patients with advanced heart failure, the presence of concomitant renal or hepatic dysfunction can pose a barrier to isolated heart transplantation. Because donor organ supply limits the availability of organ transplantation, appropriate allocation of this scarce resource is essential; thus, clear guidance for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation is urgently required. The purposes of this scientific statement are (1) to describe the impact of pretransplantation renal and hepatic dysfunction on posttransplantation outcomes; (2) to discuss the assessment of pretransplantation renal and hepatic dysfunction; (3) to provide an approach to patient selection for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation and posttransplantation management; and (4) to explore the ethics of multiorgan transplantation.
AB - Although heart transplantation is the preferred therapy for appropriate patients with advanced heart failure, the presence of concomitant renal or hepatic dysfunction can pose a barrier to isolated heart transplantation. Because donor organ supply limits the availability of organ transplantation, appropriate allocation of this scarce resource is essential; thus, clear guidance for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation is urgently required. The purposes of this scientific statement are (1) to describe the impact of pretransplantation renal and hepatic dysfunction on posttransplantation outcomes; (2) to discuss the assessment of pretransplantation renal and hepatic dysfunction; (3) to provide an approach to patient selection for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation and posttransplantation management; and (4) to explore the ethics of multiorgan transplantation.
KW - AHA Scientific Statements
KW - heart transplantation
KW - kidney transplantation
KW - liver transplantation
UR - http://www.scopus.com/inward/record.url?scp=85168500988&partnerID=8YFLogxK
U2 - 10.1161/CIR.0000000000001155
DO - 10.1161/CIR.0000000000001155
M3 - Review article
C2 - 37439224
AN - SCOPUS:85168500988
SN - 0009-7322
VL - 148
SP - 622
EP - 636
JO - Circulation
JF - Circulation
IS - 7
ER -