Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

Robyn S. Klein

doi:10.1016/j.chom.2017.06.015

Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

Robyn S. Klein

Research output: Contribution to journal › Short survey

2 Scopus citations

Abstract

Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections. Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.

Original language	English
Pages (from-to)	9-11
Number of pages	3
Journal	Cell Host and Microbe
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.chom.2017.06.015
State	Published - Jul 12 2017

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10.1016/j.chom.2017.06.015

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Klein, R. S. (2017). Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly. Cell Host and Microbe, 22(1), 9-11. https://doi.org/10.1016/j.chom.2017.06.015

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abstract = "Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections. Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.",

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