Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

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Abstract

Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections. Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.

Original languageEnglish
Pages (from-to)9-11
Number of pages3
JournalCell Host and Microbe
Volume22
Issue number1
DOIs
StatePublished - Jul 12 2017

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