Dry-reagent storage for disposable lab-on-a-card diagnosis of enteric pathogens

S. Ramachandran, J. Gerdes, P. Tarr, P. Yager, L. Dillman, R. Peck, M. Kokoris, M. Nabavi, F. Battrell, D. Hoekstra, B. H. Weigl

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

This paper presents a process for dry-reagent storage and handling for a microfluidic lab-on-a-card platform for point-of-care applications to identify enteric bacterial pathogens in patients presenting with acute diarrhea, with special reference to infections that might be encountered in developing countries. Three different reagents are studied: i) antibody-coated magnetic beads for pathogen capture, ii) lysis buffer for extraction of nucleic acids from the pathogens, and iii) DNA amplification of the nucleic acids by polymerase chain reaction. This presentation will report on the process of dry reagent storage, resuspension and its functionality.

Original languageEnglish
Title of host publicationConference Proceedings - 1st Transdisciplinary Conference on Distributed Diagnosis and Home Healthcare, D2H2 2006
Pages16-19
Number of pages4
DOIs
StatePublished - Nov 14 2006
Event1st Transdisciplinary Conference on Distributed Diagnosis and Home Healthcare, D2H2 2006 - Arlington, VA, United States
Duration: Apr 2 2006Apr 4 2006

Publication series

NameConference Proceedings - 1st Transdisciplinary Conference on Distributed Diagnosis and Home Healthcare, D2H2 2006
Volume2006

Conference

Conference1st Transdisciplinary Conference on Distributed Diagnosis and Home Healthcare, D2H2 2006
Country/TerritoryUnited States
CityArlington, VA
Period04/2/0604/4/06

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