Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules

José E. Betancourt; Chandramouleeswaran Subramani; José L. Serrano-Velez; Eduardo Rosa-Molinar; Vincent M. Rotello; José M. Rivera

doi:10.1039/c0cc04063k

Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules

José E. Betancourt
, Chandramouleeswaran Subramani
, José L. Serrano-Velez
, Eduardo Rosa-Molinar
, Vincent M. Rotello
, José M. Rivera

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

An 8-(phenyl)-2′-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.

Original language	English
Pages (from-to)	8537-8539
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	45
DOIs	https://doi.org/10.1039/c0cc04063k
State	Published - Dec 7 2010

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title = "Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules",

abstract = "An 8-(phenyl)-2′-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.",

author = "Betancourt, \{Jos{\'e} E.\} and Chandramouleeswaran Subramani and Serrano-Velez, \{Jos{\'e} L.\} and Eduardo Rosa-Molinar and Rotello, \{Vincent M.\} and Rivera, \{Jos{\'e} M.\}",

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T1 - Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules

AU - Betancourt, José E.

AU - Subramani, Chandramouleeswaran

AU - Serrano-Velez, José L.

AU - Rosa-Molinar, Eduardo

AU - Rotello, Vincent M.

AU - Rivera, José M.

PY - 2010/12/7

Y1 - 2010/12/7

N2 - An 8-(phenyl)-2′-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.

AB - An 8-(phenyl)-2′-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.

UR - https://www.scopus.com/pages/publications/78149455595

U2 - 10.1039/c0cc04063k

DO - 10.1039/c0cc04063k

M3 - Article

C2 - 20972498

AN - SCOPUS:78149455595

SN - 1359-7345

VL - 46

SP - 8537

EP - 8539

JO - Chemical Communications

JF - Chemical Communications

IS - 45

ER -

Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules

Abstract

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