@article{12f7fc93cdd243fd8e33998f9bb32233,
title = "Draft genome sequences of three β-lactam-catabolizing soil Proteobacteria",
abstract = "Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic.",
author = "Crofts, {Terence S.} and Bin Wang and Aaron Spivak and Gianoulis, {Tara A.} and Forsberg, {Kevin J.} and Gibson, {Molly K.} and Johnsky, {Lauren A.} and Broomall, {Stacey M.} and Rosenzweig, {C. Nicole} and Skowronski, {Evan W.} and Gibbons, {Henry S.} and Sommer, {Morten O.A.} and Gautam Dantasa",
note = "Funding Information: This work is supported in part by awards to G.D. through the Edward Mallinckrodt, Jr Foundation (Scholar Award) and from the NIH Director's New Innovator Award (http://commonfund.nih.gov/newinnovator/), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK [http://www.niddk.nih.gov]), the National Institute of General Medical Sciences (NIGMS [http://www.nigms.nih.gov]), and the National Institute of Allergy and Infectious Diseases (NIAID [https://www.niaid.nih.gov]) of the National Institutes of Health (NIH) under award numbers DP2DK098089, R01GM099538, and R01AI123394, respectively. T.S.C. received support from a National Institute of Child Health and Development training grant through award no. T32 HD049305 (Kelle H. Moley, principal investigator). K.J.F. received support from the NIGMS Cell and Molecular Biology Training Grant (GM 007067), the NHGRI Genome Analysis Training Program (T32 HG000045), and the NSF as a graduate research fellow (award number DGE-1143954). M.K.G. received support as a Spencer T. Olin Fellow at Washington University and from the NSF as a graduate research fellow (DGE-1143954). Sequencing through the U.S. Army Edgewood Chemical Biological Center was supported in part through funding provided by the Transformational Medical Technologies Initiative of the Defense Threat Reduction Agency, U.S. Department of Defense. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies. We are thankful to Robert Potter of the Dantas lab for general helpful discussions regarding the manuscript. Publisher Copyright: {\textcopyright} 2017 Crofts et al.",
year = "2017",
month = aug,
day = "1",
doi = "10.1128/genomeA.00653-17",
language = "English",
volume = "5",
journal = "Genome Announcements",
issn = "2169-8287",
number = "32",
}