Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer

Keyphrases

• Catenin 100%
• In Cancer 100%
• Myeloid-derived Suppressor Cells 100%
• Tumor Growth 25%
• Tumor Progression 16%
• Cellular Accumulation 16%
• Cell number 8%
• Clinical Significance 8%
• T Cell Response 8%
• Antitumor T Cells 8%
• Bone Marrow 8%
• Pancreatic Cancer 8%
• Healthy Controls 8%
• Secondary Lymphoid Organs 8%
• Cancer Patients 8%
• CD8+ T Cells 8%
• Cell Support 8%
• Constitutively Active 8%
• Cell-mediated 8%
• Anticancer Therapy 8%
• WT Mice 8%
• Tumor-bearing Mice 8%
• Cell Surface Display 8%
• Raising Concerns 8%
• Tumor Expansion 8%
• Immune-suppressive 8%
• Suppressive Activity 8%
• Tumor-bearing Host 8%
• Tumor Promotion 8%
• T Cell Inhibition 8%
• Expansion Growth 8%

Biochemistry, Genetics and Molecular Biology

• Catenin 100%
• Downregulation 100%
• Myeloid 100%
• Tumor Progression 38%
• T Cell 23%
• Wild Type Mouse 7%
• CD8 7%
• Anticancer 7%
• Cell Count 7%
• Immunity 7%

Immunology and Microbiology

• Downregulation 100%
• Catenin 100%
• Myeloid-Derived Suppressor Cell 100%
• T Cell 16%
• Myeloid 8%
• Wild Type Mouse 8%
• Lymphoid Organ 8%
• Cytotoxic T-Cell 8%
• Immunity 8%