TY - JOUR
T1 - Double lung transplantation for end-stage Kartagener syndrome
T2 - A case report and literature review
AU - Wang, Bo
AU - Zhang, Xinghua
AU - Jiang, Wenyang
AU - Huang, Jie
AU - Chen, Jingyu
AU - Kreisel, Daniel
AU - Danguilan, Jose Luis J.
AU - Hsin, Michael
AU - Lin, Huiqing
N1 - Funding Information:
The authors thank Prof. Handong Zou and Prof. Guozhong Chen for their academic and technical support. Funding: This study was supported by the National Natural Science Foundation of China (81800343).
Publisher Copyright:
© 2020 Journal of Thoracic Disease.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Kartagener syndrome (KS) is an autosomal recessive disorder characterized by situs inversus, paranasal sinusitis and bronchiectasis. We report the successful use of double lung transplant (DLTx) to treat end-stage KS. A 49-year-old Han woman was admitted to Renmin Hospital (Wuhan University, China) in September 2017 with a ≥15 year history of chronic productive cough that had worsened during the past year. Clinical examination and imaging investigations revealed respiratory failure and situs inversus consistent with KS. The patient was successfully treated with DLTx involving bilateral bronchial anastomoses. DLTx is a feasible treatment option for end-stage KS.
AB - Kartagener syndrome (KS) is an autosomal recessive disorder characterized by situs inversus, paranasal sinusitis and bronchiectasis. We report the successful use of double lung transplant (DLTx) to treat end-stage KS. A 49-year-old Han woman was admitted to Renmin Hospital (Wuhan University, China) in September 2017 with a ≥15 year history of chronic productive cough that had worsened during the past year. Clinical examination and imaging investigations revealed respiratory failure and situs inversus consistent with KS. The patient was successfully treated with DLTx involving bilateral bronchial anastomoses. DLTx is a feasible treatment option for end-stage KS.
KW - Kartagener syndrome
KW - Lung transplantation
KW - Primary ciliary dyskinesia
KW - Situs inversus
UR - http://www.scopus.com/inward/record.url?scp=85085982729&partnerID=8YFLogxK
U2 - 10.21037/jtd.2020.02.28
DO - 10.21037/jtd.2020.02.28
M3 - Review article
C2 - 32395296
AN - SCOPUS:85085982729
VL - 12
SP - 1588
EP - 1594
JO - Journal of Thoracic Disease
JF - Journal of Thoracic Disease
SN - 2072-1439
IS - 4
ER -