Double lung transplantation for end-stage Kartagener syndrome: A case report and literature review

Bo Wang, Xinghua Zhang, Wenyang Jiang, Jie Huang, Jingyu Chen, Daniel Kreisel, Jose Luis J. Danguilan, Michael Hsin, Huiqing Lin

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Kartagener syndrome (KS) is an autosomal recessive disorder characterized by situs inversus, paranasal sinusitis and bronchiectasis. We report the successful use of double lung transplant (DLTx) to treat end-stage KS. A 49-year-old Han woman was admitted to Renmin Hospital (Wuhan University, China) in September 2017 with a ≥15 year history of chronic productive cough that had worsened during the past year. Clinical examination and imaging investigations revealed respiratory failure and situs inversus consistent with KS. The patient was successfully treated with DLTx involving bilateral bronchial anastomoses. DLTx is a feasible treatment option for end-stage KS.

Original languageEnglish
Pages (from-to)1588-1594
Number of pages7
JournalJournal of Thoracic Disease
Volume12
Issue number4
DOIs
StatePublished - Apr 1 2020
Externally publishedYes

Keywords

  • Kartagener syndrome
  • Lung transplantation
  • Primary ciliary dyskinesia
  • Situs inversus

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    Wang, B., Zhang, X., Jiang, W., Huang, J., Chen, J., Kreisel, D., Danguilan, J. L. J., Hsin, M., & Lin, H. (2020). Double lung transplantation for end-stage Kartagener syndrome: A case report and literature review. Journal of Thoracic Disease, 12(4), 1588-1594. https://doi.org/10.21037/jtd.2020.02.28