Dose-related effects of alcohol on dynamic posturography and oculomotor measures

Joel A. Goebel; Douglas N. Dunham; John W. Rohrbaugh; Douglas Fischel; Paula A. Stewart

doi:10.3109/00016489509125232

Dose-related effects of alcohol on dynamic posturography and oculomotor measures

Joel A. Goebel, Douglas N. Dunham, John W. Rohrbaugh, Douglas Fischel, Paula A. Stewart

Department of Otolaryngology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Four healthy male volunteers < 30 years of age participated in a blinded study of placebo versus low (0.45 g/kg lean body weight = LBW), medium (0.80 g/kg LBW) and high (1.05 g/kg LBW) dose ethanol ingestion to investigate its effect upon gaze and posture control. Serial electronystagmography and computerized platform posturography were performed at different points along each subject's blood alcohol concentration (BAC) curve as measured by breath analysis. Smooth pursuit and positional testing revealed subtle abnormalities at sub-intoxicating BACs. In addition, instability on posturography was evident on the Sensory Organization Test with no statistically significant influence observed on muscle latency testing as determined by sway analysis. We conclude that even low ethanol BAC levels produce widespread gaze and posture control effects which can be easily documented.

Original language	English
Pages (from-to)	212-215
Number of pages	4
Journal	Acta Oto-Laryngologica
Volume	115
Issue number	S520
DOIs	https://doi.org/10.3109/00016489509125232
State	Published - 1995

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abstract = "Four healthy male volunteers < 30 years of age participated in a blinded study of placebo versus low (0.45 g/kg lean body weight = LBW), medium (0.80 g/kg LBW) and high (1.05 g/kg LBW) dose ethanol ingestion to investigate its effect upon gaze and posture control. Serial electronystagmography and computerized platform posturography were performed at different points along each subject's blood alcohol concentration (BAC) curve as measured by breath analysis. Smooth pursuit and positional testing revealed subtle abnormalities at sub-intoxicating BACs. In addition, instability on posturography was evident on the Sensory Organization Test with no statistically significant influence observed on muscle latency testing as determined by sway analysis. We conclude that even low ethanol BAC levels produce widespread gaze and posture control effects which can be easily documented.",

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AU - Goebel, Joel A.

AU - Dunham, Douglas N.

AU - Rohrbaugh, John W.

AU - Fischel, Douglas

AU - Stewart, Paula A.

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Dose-related effects of alcohol on dynamic posturography and oculomotor measures

Abstract

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