TY - JOUR
T1 - Dose calculations about shielded gynecological colpostats
AU - Williamson, Jeffrey F.
N1 - Funding Information:
Reprint requests to: Jetfrey F. Williamson, Ph.D., Washington University School of Medicine, Mallinckrodt Institute of Radiology, 5 10 So. Kingshighway Blvd., St. Louis, MO 63 110. Acknowledgements-This work was supported in part by research grants PO l-CA 17343 and RO 1-CA46640 awarded by the National Cancer Institute. The author would like to thank Bruce Lulu, Ph.D. and Wendell Lutz, Ph.D., for many helpful and stimulating conversations, Zhang Hongbin for his technical as-
PY - 1990/7
Y1 - 1990/7
N2 - Although shielded gynecological colpostats have been shown experimentally to reduce doses to bladder and rectal tissue by as much as 50%, nearly all previously described dose computation algorithms ignore applicator heterogeneities. We describe the use of realistic Monte Carlo calculations to study the dosimetric effects of applicator structure. Use of sophisticated solid modeling techniques allows the complex internal structure of two commercially-available Fletcher-Suit colpostats, as well as that of 226Ra or 137Cs tubes, to be accurately simulated. Our results show significant differences among these source-applicator combinations. In addition, a novel dose computation algorithm for efficiently estimating absorbed dose near shielded applicators is described. Our approach is based upon empirical separation of primary- and scatter-dose components. The algorithm requires a small base of Monte Carlo-generated data, reproduces the Monte Carlo dose estimates within 3%, and is faster than Monte Carlo by a factor of 15,000. The scatter-separation method has the potential to make accurate dose estimates to bladder, rectum, tumor, and vagina available for clinical treatment planning and for extraction of more meaningful dose-response curves from clinical data.
AB - Although shielded gynecological colpostats have been shown experimentally to reduce doses to bladder and rectal tissue by as much as 50%, nearly all previously described dose computation algorithms ignore applicator heterogeneities. We describe the use of realistic Monte Carlo calculations to study the dosimetric effects of applicator structure. Use of sophisticated solid modeling techniques allows the complex internal structure of two commercially-available Fletcher-Suit colpostats, as well as that of 226Ra or 137Cs tubes, to be accurately simulated. Our results show significant differences among these source-applicator combinations. In addition, a novel dose computation algorithm for efficiently estimating absorbed dose near shielded applicators is described. Our approach is based upon empirical separation of primary- and scatter-dose components. The algorithm requires a small base of Monte Carlo-generated data, reproduces the Monte Carlo dose estimates within 3%, and is faster than Monte Carlo by a factor of 15,000. The scatter-separation method has the potential to make accurate dose estimates to bladder, rectum, tumor, and vagina available for clinical treatment planning and for extraction of more meaningful dose-response curves from clinical data.
KW - Brachytherapy
KW - Colpostats
KW - Cs
KW - Dosimetry
KW - Intracavitary therapy
KW - Monte Carlo
KW - Ra
UR - http://www.scopus.com/inward/record.url?scp=0025334388&partnerID=8YFLogxK
U2 - 10.1016/0360-3016(90)90150-I
DO - 10.1016/0360-3016(90)90150-I
M3 - Article
C2 - 2380082
AN - SCOPUS:0025334388
SN - 0360-3016
VL - 19
SP - 167
EP - 178
JO - International journal of radiation oncology, biology, physics
JF - International journal of radiation oncology, biology, physics
IS - 1
ER -