Dopamine transporter imaging with novel, selective cocaine analogs

U. Scheffel; R. F. Dannals; D. F. Wong; F. Yokoi; F. I. Carroll; M. J. Kuhar

doi:10.1097/00001756-199211000-00005

Dopamine transporter imaging with novel, selective cocaine analogs

U. Scheffel, R. F. Dannals, D. F. Wong, F. Yokoi, F. I. Carroll, M. J. Kuhar

Precision Radiotheranostics Translation Center (PRTC)

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

Original language	English
Pages (from-to)	969-972
Number of pages	4
Journal	NeuroReport
Volume	3
Issue number	11
DOIs	https://doi.org/10.1097/00001756-199211000-00005
State	Published - Nov 1992

Keywords

Cocaine
Dopamine transporter
Dopamine uptake
RTI-121
RTI-122
RTI-55
SPECT imaging

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10.1097/00001756-199211000-00005

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title = "Dopamine transporter imaging with novel, selective cocaine analogs",

abstract = "RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.",

keywords = "Cocaine, Dopamine transporter, Dopamine uptake, RTI-121, RTI-122, RTI-55, SPECT imaging",

author = "U. Scheffel and Dannals, \{R. F.\} and Wong, \{D. F.\} and F. Yokoi and Carroll, \{F. I.\} and Kuhar, \{M. J.\}",

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T1 - Dopamine transporter imaging with novel, selective cocaine analogs

AU - Scheffel, U.

AU - Dannals, R. F.

AU - Wong, D. F.

AU - Yokoi, F.

AU - Carroll, F. I.

AU - Kuhar, M. J.

PY - 1992/11

Y1 - 1992/11

N2 - RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

AB - RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

KW - Cocaine

KW - Dopamine transporter

KW - Dopamine uptake

KW - RTI-121

KW - RTI-122

KW - RTI-55

KW - SPECT imaging

UR - https://www.scopus.com/pages/publications/0026441542

U2 - 10.1097/00001756-199211000-00005

DO - 10.1097/00001756-199211000-00005

M3 - Article

C2 - 1482766

AN - SCOPUS:0026441542

SN - 0959-4965

VL - 3

SP - 969

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JO - NeuroReport

JF - NeuroReport

IS - 11

ER -

Dopamine transporter imaging with novel, selective cocaine analogs

Abstract

Keywords

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