Do Current Animal Models of Intracerebral Hemorrhage Mirror the Human Pathology?

Opeolu Adeoye, Joseph F. Clark, Pooja Khatri, Kenneth R. Wagner, Mario Zuccarello, Gail J. Pyne-Geithman

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Although intracerebral hemorrhage (ICH) has no proven treatment, well-designed studies using animal models of ICH may lead to the development of novel therapies. We briefly review current animal models of ICH. Furthermore, we discuss how these models may be utilized and targeted to facilitate translation of preclinical findings to the clinical arena.

Original languageEnglish
Pages (from-to)17-25
Number of pages9
JournalTranslational Stroke Research
Volume2
Issue number1
DOIs
StatePublished - Mar 2011

Keywords

  • Animal models
  • Intracerebral hemorrhage
  • Stroke
  • Translation

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